Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 9/20 | 0.45 |
| ▸ | CTSS | P25774 | 6/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819517 | 1.00 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL1341495 | 1.00 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL7079252 | 0.91 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL6237621 | 0.91 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL9039507 | 0.89 | CTSK (0.42) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL9037870 | 0.89 | CTSK (0.42) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL370241 | 0.88 | KMT2A (0.43) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL28948917 | 0.88 | KMT2A (0.43) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL28948914 | 0.87 | CTSL (0.56) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL26818450 | 0.87 | CTSL (0.56) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240252477-A1 | NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF | UNIVERSITA' DEGLI STUDI DI TORINO (60%) (IT) | 2024-08-01 | — | — | US | claimed |
| CN-116162255-B | Charge-convertible dendrimer and preparation method thereof | 东莞理工学院 | 2024-07-09 | — | — | CN | claimed |
| CN-117867481-A | High-stability cyanide-free electroless reduced gold plating solution | 江苏矽智半导体科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| EP-4334287-A1 | NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF | Università Degli Studi Di Torino (IT) | 2024-03-13 | — | — | EP | claimed |
| CN-116789579-A | Preparation method of ultrafast metal-free solvent-free disulfide bond-containing compound | 南京工业大学 | 2023-09-22 | — | — | CN | claimed |
| CN-116162255-A | Charge-convertible dendrimer and preparation method thereof | 东莞理工学院 | 2023-05-26 | — | — | CN | claimed |
| WO-2022234447-A1 | NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF | UNIVERSITA' DEGLI STUDI DI TORINO (IT) | 2022-11-10 | — | — | WO | claimed |
| CN-103852511-B | Electrophoresis-mediated microanalysis determination method for chiral separation of arginine in pharmaceutical preparation | 上海市食品药品检验所 | 2018-05-22 | — | — | CN | claimed |
| US-20030077059-A1 | Optical fiber coating compositions | CORNING INCORPORATED | 2003-04-24 | — | — | US | claimed |
| US-RE50899-E1 | Small diameter low attenuation optical fiber | CORNING INCORPORATED (US) | 2026-05-26 | — | — | US | disclosed |
| US-12486241-B2 | Cystine diamide analogs for cystinuria | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-12-02 | — | — | US | disclosed |
| US-12479933-B2 | Crosslinked alginic acid structure | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2025-11-25 | — | — | US | disclosed |
| US-12377164-B2 | Linkers and conjugates | ASTRAZENECA AB (SE) | 2025-08-05 | — | — | US | disclosed |
| EP-4587029-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES | Invea Therapeutics, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| US-6284910-B1 | FARNESYL TRANSFERASE INHIBITORS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2001-09-04 | — | — | US | disclosed |
| US-6268339-B1 | Lanthionine bridged peptides | Kolbeck, Winfried (DE) | 2001-07-31 | — | — | US | disclosed |
| US-6046235-A | SULFUR-CONTAINING AMINO ACID DERIVATIVES WHICH HAVE INHIBITORY EFFECTS ON LEUKOTRIENE A4 HYDROLASE AND USEFUL AS THERAPEUTICAL AGENTS FOR INFLAMMATORY DISEASES SUCH AS RHEUMATISM, PSORIASIS, GOUT, CYSTIC FIBROSIS AND BOWL DISEASES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| US-6028168-A | Lanthionine bridged peptides | WINFRIED KOLBECK (DE) | 2000-02-22 | — | — | US | disclosed |
| EP-0947502-A1 | NOVEL SULFUR-CONTAINING AMINO ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5874549-A | A METABOLIZABLE BICYCLIC, NON-AROMATIC HYDROCARBON COMPOUND TO A FREE CARBOXYL GROUP, ACID-CLEAVABLY LINKS AN AMIDE-CONTAINING ACTIVE AGENT TO A TARGETING AGENT FOR USE AS DRUG DELIVERY, DRUG CARRIER | NEORX CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12486241-B2 | Cystine diamide analogs for cystinuria | CTH, CBS, SLC7A11 | CYP1A2 4197/4885CYP2C9 3077/4885CYP2C19 3402/4885 |
| US-20240252477-A1 | NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF | NLRP3, PYCARD, NLRP1 | CYP1A2 1481/4885CYP2C9 3588/4885CYP2C19 3279/4885 |
| US-12377164-B2 | Linkers and conjugates | F13A1, NGLY1, SPPL2A | CYP1A2 4213/4885CYP2C9 4477/4885CYP2C19 4653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.