SCHEMBL29590852

SCHEMBL29590852

CC(C)[C@H](N)C(=O)N[C@@H](CCCNC(N)=O)C(=O)NCC(=O)N(C)CC(=O)O

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GLO1 Q04760 1/20 0.36
▸ C3AR1 Q16581 1/20 0.33
▸ DPP4 P27487 2/20 0.33
▸ DPP8 Q6V1X1 2/20 0.33
▸ DPP9 Q86TI2 2/20 0.33
▸ DPP7 Q9UHL4 2/20 0.33
▸ SIRT5 Q9NXA8 1/20 0.33
▸ FURIN P09958 4/20 0.32
▸ SIRT6 Q8N6T7 1/20 0.31
▸ SIRT1 Q96EB6 1/20 0.31
▸ TACR1 P25103 1/20 0.31
▸ FAP Q12884 1/20 0.30
▸ QRFPR Q96P65 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29589410 0.87 NMT2 (0.39) GLO1DPP4DPP8DPP9DPP7
SCHEMBL29590144 0.86 GLO1 (0.39) GLO1C3AR1DPP4DPP8DPP9
SCHEMBL21503894 0.85 DPP4 (0.33) GLO1DPP4DPP8DPP9DPP7
SCHEMBL30550554 0.81 DPP7 (0.42) GLO1C3AR1DPP7
SCHEMBL22927849 0.79 DPP4 (0.36) C3AR1DPP4DPP8DPP9DPP7
SCHEMBL29589433 0.79 DPP4 (0.37) GLO1DPP4DPP8DPP9DPP7
SCHEMBL16862522 0.78 C3AR1 (0.46) C3AR1DPP4DPP8DPP9DPP7
SCHEMBL28819908 0.78 C3AR1 (0.46) C3AR1DPP4DPP8DPP9DPP7
SCHEMBL6047671 0.78 C3AR1 (0.46) C3AR1DPP4DPP8DPP9DPP7
SCHEMBL29359380 0.78 C3AR1 (0.46) C3AR1DPP4DPP8DPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 — — US claimed
US-11957760-B2 Folate receptor targeted nanoparticle drug conjugates and uses thereof ELUCIDA ONCOLOGY, INC. (US) 2024-04-16 — — US disclosed
EP-4257156-A2 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF Elucida Oncology, Inc. (US) 2023-10-11 — — EP disclosed
EP-4237008-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF Elucida Oncology, Inc. (US) 2023-09-06 — — EP disclosed
US-20230263899-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-24 — — US disclosed
US-20230263898-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-24 — — US disclosed
EP-4103236-B1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY INC (US) 2023-08-16 — — EP disclosed
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 — — US disclosed
EP-4103236-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF Elucida Oncology, Inc. (US) 2022-12-21 — — EP disclosed
US-20220378924-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2022-12-01 — — US disclosed
WO-2022093793-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 — — WO disclosed
WO-2022093800-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220378924-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF FOLR1, FOLR2, DHFR GLO1 2489/4885C3AR1 1865/4885DPP4 3889/4885
US-11957760-B2 Folate receptor targeted nanoparticle drug conjugates and uses thereof FOLR1, FOLR2, DHFR GLO1 2489/4885C3AR1 1865/4885DPP4 3889/4885
US-20230263899-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF FOLR1, FOLR2, DHFR GLO1 2489/4885C3AR1 1865/4885DPP4 3889/4885
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF NDC1, KIFC1, SDCBP GLO1 2431/4885C3AR1 3148/4885DPP4 3437/4885
US-20230263898-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF FOLR1, FOLR2, DHFR GLO1 2489/4885C3AR1 1865/4885DPP4 3889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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