Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24499499 | 1.00 | ALDH1A1 (0.48) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL24499494 | 0.83 | PDCD1 (0.50) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL4505316 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL368306 | 0.80 | IKBKB (0.49) | FGFR1FGFR3MAPK1IKBKBCHUK | |
| SCHEMBL30205037 | 0.79 | LMNA (0.49) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL6927417 | 0.78 | FGFR1 (0.58) | ALDH1A1KMT2AGAALMNACFTR | |
| SCHEMBL15975999 | 0.75 | SLC6A3 (0.52) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL21410018 | 0.75 | ALDH1A1 (0.54) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL25973455 | 0.74 | TDO2 (0.48) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL2003190 | 0.74 | KDM4E (0.50) | ALDH1A1HPGDGAAMAPTCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255902-A1 | 2,3-DIHYDRO-4H-BENZO[B][1,4]OXAZIN-4-YL)(5-(PHENYL)-PYRIDIN-3-YL)METHANONE DERIVATIVES AND SIMILAR COMPOUNDS AS CYP11A1 INHIBITORS FOR THE TREATMENT OF PROSTATE CANCER | Orion Corporation (FI) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022117920-A1 | 2,3-DIHYDRO-4H-BENZO[B][1,4]OXAZIN-4-YL)(5-(PHENYL)-PYRIDIN-3-YL)METHANONE DERIVATIVES AND SIMILAR COMPOUNDS AS CYP11A1 INHIBITORS FOR THE TREATMENT OF PROSTATE CANCER | ORION CORPORATION (FI) | 2022-06-09 | — | — | WO | disclosed |