Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31490068 | 1.00 | CA2 (0.55) | CA2CA12CA1CA5ACA9 | |
| SCHEMBL7996869 | 0.92 | PTPN1 (0.50) | CA2CA12CA1CA5ACA9 | |
| SCHEMBL2453696 | 0.90 | CA2 (0.52) | CA2CA12CA1CA5ACA9 | |
| SCHEMBL4860328 | 0.89 | CA2 (0.51) | CA2CA12CA1CA5ACA9 | |
| SCHEMBL13250641 | 0.88 | HIF1A (0.45) | CA2CA12CA1CA5ACA9 | |
| SCHEMBL10451442 | 0.86 | PTGS2 (0.50) | CA2CA12CA1CA5ACA9 | |
| SCHEMBL15136763 | 0.86 | ALDH1A1 (0.44) | CA2CA12CA1CA5ACA9 | |
| SCHEMBL10620436 | 0.85 | CA2 (0.61) | CA2CA12CA1CA5ACA9 | |
| SCHEMBL5937259 | 0.85 | KDM4E (0.53) | SMN1; SMN2KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2592712 | 0.84 | CA2 (0.60) | CA2CA12CA1CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3761950-B1 | BIOISPIRED PROTEASOME ACTIVATORS WITH ANTIAGEING ACTIVITY | IOULIA & IRENE TSETI PHARMACEUTICAL LABORATORIES IND AND COMMERCIAL S A (GR) | 2025-04-09 | — | — | EP | disclosed |
| US-20230063230-A1 | NURR1 RECEPTOR MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-03-02 | — | — | US | disclosed |
| EP-3927330-A1 | NURR1 RECEPTOR MODULATORS | The Regents of the University of California (US) | 2021-12-29 | — | — | EP | disclosed |
| EP-3761950-A1 | BIOISPIRED PROTEASOME ACTIVATORS WITH ANTIAGEING ACTIVITY | IOULIA AND IRENE TSETI Pharmaceutical Laboratories S.A. (GR) | 2021-01-13 | — | — | EP | disclosed |
| WO-2019171088-A1 | BIOISPIRED PROTEASOME ACTIVATORS WITH ANTIAGEING ACTIVITY | NATIONAL HELLENIC RESEARCH FOUNDATION (GR) | 2019-09-12 | — | — | WO | disclosed |
| US-7772229-B2 | Oxabispidine compounds useful in the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2010-08-10 | — | — | US | disclosed |
| US-20100004459-A1 | 2-PHENYLNICOTINIC ACID DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2010-01-07 | — | — | US | disclosed |
| US-20090326221-A1 | New oxabispidine compunds useful in the treatment of cardiac arrhythmias | ASTRAZENECA AB, (SE) | 2009-12-31 | — | — | US | disclosed |
| EP-2128136-A1 | 2-PHENYLNICOTINIC ACID DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2009-12-02 | — | — | EP | disclosed |
| CN-101265262-A | New oxabispidine compounds useful in the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2008-09-17 | — | — | CN | disclosed |
| US-20020137766-A1 | Azabicyclooctane derivatives useful in the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | US | disclosed |
| EP-1235831-A2 | NEW OXABISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | AstraZeneca AB (SE) | 2002-09-04 | — | — | EP | disclosed |
| WO-2002009706-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |
| WO-2001028992-A2 | NEW OXABISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2001-04-26 | — | — | WO | disclosed |
| EP-0700385-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027967-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1994-12-08 | — | — | WO | disclosed |
| EP-0256888-B1 | BENZOTHIAZEPINE VASODILATORS HAVING ARALKYL SUBSTITUTION | McNeilab, Inc. (US) | 1991-07-03 | — | — | EP | disclosed |
| US-4937373-A | Substituted naphthalene carboxylic acids | HOFFMANN-LA ROCHE INC. (US) | 1990-06-26 | — | — | US | disclosed |
| US-4729994-A | Benzothiazepine vasodilators having aralkyl substitution | MCNEILAB, INC. (US) | 1988-03-08 | — | — | US | disclosed |
| EP-0256888-A1 | Benzothiazepine vasodilators having aralkyl substitution | McNeilab, Inc. (US) | 1988-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326221-A1 | New oxabispidine compunds useful in the treatment of cardiac arrhythmias | KCNH1, CACNA1E, SCN1B | CA2 2213/4885CA12 3283/4885CA1 1625/4885 |
| US-20100004459-A1 | 2-PHENYLNICOTINIC ACID DERIVATIVE | XDH, NUDT1, PNPO | CA2 2808/4885CA12 4815/4885CA1 4743/4885 |
| US-20230063230-A1 | NURR1 RECEPTOR MODULATORS | NR2E3, NR4A2, NR0B1 | CA2 4851/4885CA12 4762/4885CA1 4527/4885 |
| US-20020137766-A1 | Azabicyclooctane derivatives useful in the treatment of cardiac arrhythmias | KCNH1, KCNH2, KCNH3 | CA2 2353/4885CA12 2908/4885CA1 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.