SCHEMBL29600101

SCHEMBL29600101

CCOC(=O)CNC(=O)C(C(C)C)N(C(C)=O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.40
ALOX15 P16050 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
ALOX12 P18054 1/20 0.40
ATM Q13315 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
POLB P06746 2/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 4/20 0.39
IDH1 O75874 1/20 0.39
THRB P10828 1/20 0.38
F2 P00734 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2B Q13224 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5598191 1.00 NPSR1 (0.40) NPSR1ALOX15GAAMAPTALOX12
SCHEMBL5598193 1.00 NPSR1 (0.40) NPSR1ALOX15GAAMAPTALOX12
SCHEMBL18546019 0.91 NPSR1 (0.43) NPSR1GAAMAPTSMN1; SMN2POLB
SCHEMBL942690 0.87 GPR139 (0.42) NPSR1SMN1; SMN2POLBKMT2AALDH1A1
SCHEMBL29600045 0.87 GPR139 (0.42) NPSR1SMN1; SMN2POLBKMT2AALDH1A1
SCHEMBL1170578 0.87 GPR139 (0.42) NPSR1SMN1; SMN2POLBKMT2AALDH1A1
SCHEMBL15016758 0.87 ALDH1A1 (0.43) NPSR1MAPTSMN1; SMN2POLBKMT2A
SCHEMBL17860509 0.86 MAPT (0.39) GAAMAPTSMN1; SMN2POLBALDH1A1
SCHEMBL3746187 0.84 CYP3A4 (0.42) NPSR1GAAPOLBKMT2AALDH1A1
SCHEMBL17860521 0.83 PDCD1 (0.40) ALOX15GAAMAPTSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220296488-A1 COMPOSITIONS COMPRISING AT LEAST ONE COMPOUND OF THE N-ACYLAMINO AMIDE FAMILY AND AT LEAST ONE ALKYL POLYGLYCOSIDE L'OREAL (FR) 2022-09-22 US claimed
EP-3986368-A1 COMPOSITIONS COMPRISING AT LEAST ONE COMPOUND OF THE N-ACYLAMINO AMIDE FAMILY AND AT LEAST ONE ALKYL POLYGLYCOSIDE L'OREAL (FR) 2022-04-27 EP claimed
US-11730682-B2 Self-standing cosmetic sheet L'OREAL (FR) 2023-08-22 US disclosed
US-20220296488-A1 COMPOSITIONS COMPRISING AT LEAST ONE COMPOUND OF THE N-ACYLAMINO AMIDE FAMILY AND AT LEAST ONE ALKYL POLYGLYCOSIDE L'OREAL (FR) 2022-09-22 US disclosed
EP-3986368-A1 COMPOSITIONS COMPRISING AT LEAST ONE COMPOUND OF THE N-ACYLAMINO AMIDE FAMILY AND AT LEAST ONE ALKYL POLYGLYCOSIDE L'OREAL (FR) 2022-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220296488-A1 COMPOSITIONS COMPRISING AT LEAST ONE COMPOUND OF THE N-ACYLAMINO AMIDE FAMILY AND AT LEAST ONE ALKYL POLYGLYCOSIDE CUTA, KRT18, UGCG NPSR1 3424/4885ALOX15 1182/4885GAA 423/4885
US-11730682-B2 Self-standing cosmetic sheet CUTA, DSG1, SUCLG1 NPSR1 734/4885ALOX15 2168/4885GAA 2712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.