Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170578 | 1.00 | GPR139 (0.42) | GPR139NPSR1CTSLALDH1A1POLB | |
| SCHEMBL29600045 | 1.00 | GPR139 (0.42) | GPR139NPSR1CTSLALDH1A1POLB | |
| SCHEMBL5797164 | 0.91 | MEN1 (0.41) | GPR139ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL18546019 | 0.90 | NPSR1 (0.43) | GPR139NPSR1CTSLALDH1A1POLB | |
| SCHEMBL15016758 | 0.89 | ALDH1A1 (0.43) | GPR139NPSR1CTSLALDH1A1POLB | |
| SCHEMBL5598191 | 0.87 | NPSR1 (0.40) | GPR139NPSR1ALDH1A1POLBHTT | |
| SCHEMBL29600101 | 0.87 | NPSR1 (0.40) | GPR139NPSR1ALDH1A1POLBHTT | |
| SCHEMBL5598193 | 0.87 | NPSR1 (0.40) | GPR139NPSR1ALDH1A1POLBHTT | |
| SCHEMBL17848959 | 0.84 | MME (0.37) | ALDH1A1CYP3A4TP53OPRM1 | |
| SCHEMBL17848960 | 0.84 | MME (0.37) | ALDH1A1CYP3A4TP53OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220296488-A1 | COMPOSITIONS COMPRISING AT LEAST ONE COMPOUND OF THE N-ACYLAMINO AMIDE FAMILY AND AT LEAST ONE ALKYL POLYGLYCOSIDE | L'OREAL (FR) | 2022-09-22 | — | — | US | claimed |
| EP-3986368-A1 | COMPOSITIONS COMPRISING AT LEAST ONE COMPOUND OF THE N-ACYLAMINO AMIDE FAMILY AND AT LEAST ONE ALKYL POLYGLYCOSIDE | L'OREAL (FR) | 2022-04-27 | — | — | EP | claimed |
| CN-113939264-A | Composition comprising at least one compound of the N-acylaminoamide family and at least one alkylpolyglycoside | 莱雅公司 | 2022-01-14 | — | — | CN | claimed |
| WO-2020254645-A1 | Compositions comprising at least one compound of the N-acylamino amide family and at least one alkyl polyglycoside | L'OREAL (FR) | 2020-12-24 | — | — | WO | claimed |
| EP-1889642-B1 | Cosmetic compositions combining a C-glycoside derivative and a N-acylaminoamide derivative | OREAL (FR) | 2019-05-08 | — | — | EP | claimed |
| US-20130139841-A1 | Method for Caring for and/or Making-up Wrinkles | L'OREAL (FR) | 2013-06-06 | — | — | US | claimed |
| US-7998933-B2 | Process for treating the skin comprising applying to the skin at least one composition comprising at least one N-aminoacylamide | L'OREAL S.A. (FR) | 2011-08-16 | — | — | US | claimed |
| US-20110021438-A1 | NOVEL COMPOUNDS OF THE N-ACYLAMINO-AMIDE FAMILY, COMPOSITIONS COMPRISING THEM AND USES THEREOF | L'OREAL S.A. (FR) | 2011-01-27 | — | — | US | claimed |
| US-7838020-B2 | Cosmetic or dermatological composition comprising an association between a compound of the N-acylaminoamide family and at least one matrix metalloproteinase inhibitor | L'OREAL (FR) | 2010-11-23 | — | — | US | claimed |
| US-7786321-B2 | Compounds of the N-acylamino amide family compositions comprising them and uses thereof | L'OREAL S.A. (FR) | 2010-08-31 | — | — | US | claimed |
| US-6998129-B2 | Cosmetic or dermatological composition comprising an association between an elastase inhibitor compound of the N-acylaminoamide family and at least one anti-inflammatory compound | L'OREAL (FR) | 2006-02-14 | — | — | US | claimed |
| US-6987128-B2 | Compounds of the N-acylamino amide family, compositions comprising same, and uses | L'OREAL S.A. (FR) | 2006-01-17 | — | — | US | claimed |
| US-20050142081-A1 | Cosmetic or dermatological composition comprising an association between a compound of the N-acylaminoamide family and at least on matrix metalloproteinase inhibitor | L'OREAL (FR) | 2005-06-30 | — | — | US | claimed |
| US-6884425-B2 | Cosmetic or dermatological composition comprising an association between a compound of the N-acylaminoamide family and at least one matrix metalloproteinase inhibitor | L'OREAL (FR) | 2005-04-26 | — | — | US | claimed |
| US-20040191203-A1 | Cosmetic or dermatological composition comprising n-acylaminoamide derivatives | L'OREAL (FR) | 2004-09-30 | — | — | US | claimed |
| EP-1292608-B1 | NOVEL COMPOUNDS OF THE N-ACYLAMINO-AMIDE FAMILY, COMPOSITIONS COMPRISING SAME, AND USES | OREAL (FR) | 2004-07-21 | — | — | EP | claimed |
| US-20030152596-A1 | Cosmetic or dermatological composition comprising of a combination of an elastase inhibitor of the N-acylaminoamide family and at least one antifungal agent or at least one antibacterial agent | L'OREAL (FR) | 2003-08-14 | — | — | US | claimed |
| US-20030152600-A1 | Novel compounds of the n-acylamino-amide-family, cpmpositions comprising same, and uses | L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | claimed |
| US-20030072732-A1 | Cosmetic or dermatological composition comprising an association between an elastase inhibitor compound of the N-acylaminoamide family and at least one anti-inflammatory compound | L'OREAL (FR) | 2003-04-17 | — | — | US | claimed |
| US-20030044438-A1 | Cosmetic or dermatological composition comprising an association between a compound of the N-acylaminoamide family and at least one matrix metalloproteinase inhibitor | L'OREAL (FR) | 2003-03-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030044438-A1 | Cosmetic or dermatological composition comprising an association between a compound of the N-acylaminoamide family and at least one matrix metalloproteinase inhibitor | SERPINB1, ELANE, MMP7 | GPR139 3155/4885NPSR1 3950/4885CTSL 347/4885 |
| US-20220296488-A1 | COMPOSITIONS COMPRISING AT LEAST ONE COMPOUND OF THE N-ACYLAMINO AMIDE FAMILY AND AT LEAST ONE ALKYL POLYGLYCOSIDE | CUTA, KRT18, UGCG | GPR139 575/4885NPSR1 3424/4885CTSL 3525/4885 |
| US-20040191203-A1 | Cosmetic or dermatological composition comprising n-acylaminoamide derivatives | AADAC, ELANE, NAAA | GPR139 3131/4885NPSR1 3914/4885CTSL 301/4885 |
| US-20050142081-A1 | Cosmetic or dermatological composition comprising an association between a compound of the N-acylaminoamide family and at least on matrix metalloproteinase inhibitor | SERPINB1, ELANE, MMP7 | GPR139 3070/4885NPSR1 4029/4885CTSL 339/4885 |
| US-20030152596-A1 | Cosmetic or dermatological composition comprising of a combination of an elastase inhibitor of the N-acylaminoamide family and at least one antifungal agent or at least one antibacterial agent | ELANE, SERPINB1, AADAC | GPR139 3966/4885NPSR1 3840/4885CTSL 249/4885 |
| US-20110021438-A1 | NOVEL COMPOUNDS OF THE N-ACYLAMINO-AMIDE FAMILY, COMPOSITIONS COMPRISING THEM AND USES THEREOF | COL2A1, COL14A1, AADAC | GPR139 2183/4885NPSR1 3538/4885CTSL 2428/4885 |
| US-20030152600-A1 | Novel compounds of the n-acylamino-amide-family, cpmpositions comprising same, and uses | COL1A1, COL14A1, COL2A1 | GPR139 1981/4885NPSR1 2249/4885CTSL 490/4885 |
| US-20030072732-A1 | Cosmetic or dermatological composition comprising an association between an elastase inhibitor compound of the N-acylaminoamide family and at least one anti-inflammatory compound | SERPINB1, ELANE, AADAC | GPR139 2376/4885NPSR1 3507/4885CTSL 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.