Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29600101 | 1.00 | NPSR1 (0.40) | NPSR1ALOX15GAAMAPTALOX12 | |
| SCHEMBL5598193 | 1.00 | NPSR1 (0.40) | NPSR1ALOX15GAAMAPTALOX12 | |
| SCHEMBL18546019 | 0.91 | NPSR1 (0.43) | NPSR1GAAMAPTSMN1; SMN2POLB | |
| SCHEMBL942690 | 0.87 | GPR139 (0.42) | NPSR1SMN1; SMN2POLBKMT2AALDH1A1 | |
| SCHEMBL29600045 | 0.87 | GPR139 (0.42) | NPSR1SMN1; SMN2POLBKMT2AALDH1A1 | |
| SCHEMBL1170578 | 0.87 | GPR139 (0.42) | NPSR1SMN1; SMN2POLBKMT2AALDH1A1 | |
| SCHEMBL15016758 | 0.87 | ALDH1A1 (0.43) | NPSR1MAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL17860509 | 0.86 | MAPT (0.39) | GAAMAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL3746187 | 0.84 | CYP3A4 (0.42) | NPSR1GAAPOLBKMT2AALDH1A1 | |
| SCHEMBL17860521 | 0.83 | PDCD1 (0.40) | ALOX15GAAMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110128500-B | Ugi mixed solvent process for preparing alpha-amido amides | 杭州迈世腾药物科技有限公司 | 2020-12-22 | — | — | CN | claimed |
| CN-110128500-B | Ugi mixed solvent process for preparing alpha-amido amides | 杭州迈世腾药物科技有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-110128500-B | Ugi mixed solvent process for preparing alpha-amido amides | 杭州迈世腾药物科技有限公司 | 2020-12-22 | — | — | CN | disclosed |
| US-7998933-B2 | Process for treating the skin comprising applying to the skin at least one composition comprising at least one N-aminoacylamide | L'OREAL S.A. (FR) | 2011-08-16 | — | — | US | disclosed |
| US-20110021438-A1 | NOVEL COMPOUNDS OF THE N-ACYLAMINO-AMIDE FAMILY, COMPOSITIONS COMPRISING THEM AND USES THEREOF | L'OREAL S.A. (FR) | 2011-01-27 | — | — | US | disclosed |
| US-7838020-B2 | Cosmetic or dermatological composition comprising an association between a compound of the N-acylaminoamide family and at least one matrix metalloproteinase inhibitor | L'OREAL (FR) | 2010-11-23 | — | — | US | disclosed |
| US-7838020-B2 | Cosmetic or dermatological composition comprising an association between a compound of the N-acylaminoamide family and at least one matrix metalloproteinase inhibitor | L'OREAL (FR) | 2010-11-23 | — | — | US | disclosed |
| EP-1269990-B1 | Cosmetic or dermatological composition comprising acylaminoamide derivatives | OREAL (FR) | 2010-10-13 | — | — | EP | disclosed |
| US-7786321-B2 | Compounds of the N-acylamino amide family compositions comprising them and uses thereof | L'OREAL S.A. (FR) | 2010-08-31 | — | — | US | disclosed |
| US-7786321-B2 | Compounds of the N-acylamino amide family compositions comprising them and uses thereof | L'OREAL S.A. (FR) | 2010-08-31 | — | — | US | disclosed |
| US-20080293962-A1 | Novel compounds of the N-acylamino amide family compositions comprising them and uses thereof | L'OREAL S.A. (FR) | 2008-11-27 | — | — | US | disclosed |
| US-20080293962-A1 | Novel compounds of the N-acylamino amide family compositions comprising them and uses thereof | L'OREAL S.A. (FR) | 2008-11-27 | — | — | US | disclosed |
| US-7419970-B2 | Aging resistance; controlling skin elasticity; example: ethyl {2-[acetyl(3-trifluoromethyl-phenyl)amino]-3-methylbutyrylamino}acetate; of slowing down the degradation activity of the elastic fibres of the intercellular spaces, may make it possible to reduce this phenomenon of accelerated ageing of skin | L'OREAL (FR) | 2008-09-02 | — | — | US | disclosed |
| EP-1269988-B1 | Cosmetic or dermatological composition comprising acylaminoamide derivatives | OREAL (FR) | 2007-12-05 | — | — | EP | disclosed |
| US-20070202203-A1 | ANTI-AGEING COMPOSITION | L'OREAL (FR) | 2007-08-30 | — | — | US | disclosed |
| EP-1275372-B1 | Cosmetic or dermatological composition comprising a N-acylaminoamide derivative and a metalloproteinase inhibitor | OREAL (FR) | 2007-06-13 | — | — | EP | disclosed |
| EP-1399113-B1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING N-ACYLAMINOAMIDE DERIVATIVES | OREAL (FR) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293962-A1 | Novel compounds of the N-acylamino amide family compositions comprising them and uses thereof | AADAC, COL14A1, COL2A1 | NPSR1 3401/4885ALOX15 1157/4885GAA 934/4885 |
| US-20110021438-A1 | NOVEL COMPOUNDS OF THE N-ACYLAMINO-AMIDE FAMILY, COMPOSITIONS COMPRISING THEM AND USES THEREOF | COL2A1, COL14A1, AADAC | NPSR1 3538/4885ALOX15 1071/4885GAA 679/4885 |
| US-20070202203-A1 | ANTI-AGEING COMPOSITION | GLA, CUTA, CD44 | NPSR1 2258/4885ALOX15 241/4885GAA 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.