Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 19/20 | 0.63 |
| ▸ | CTSG | P08311 | 1/20 | 0.63 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3935567 | 0.91 | ELANE (0.67) | ELANECTSGCMA1 | |
| SCHEMBL20943188 | 0.91 | ELANE (0.67) | ELANECTSGCMA1 | |
| SCHEMBL3935563 | 0.91 | ELANE (0.67) | ELANECTSGCMA1 | |
| SCHEMBL20943154 | 0.91 | ELANE (0.67) | ELANECTSGCMA1 | |
| SCHEMBL30583172 | 0.91 | ELANE (0.67) | ELANECTSGCMA1 | |
| SCHEMBL17378380 | 0.86 | ELANE (0.68) | ELANECTSGCMA1 | |
| SCHEMBL7310675 | 0.86 | ELANE (0.80) | ELANECTSGCMA1 | |
| SCHEMBL18880036 | 0.86 | ELANE (0.68) | ELANECTSGCMA1 | |
| SCHEMBL20943178 | 0.86 | ELANE (0.65) | ELANECTSGCMA1 | |
| SCHEMBL8251369 | 0.86 | ELANE (0.71) | ELANECTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4004548-B1 | METHODS OF TREATING AND DIAGNOSING LUNG CANCER | YEDA RES & DEV (IL) | 2026-01-14 | — | — | EP | disclosed |
| US-20250354993-A1 | METHODS OF TREATING AND DIAGNOSING LUNG CANCER | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2025-11-20 | — | — | US | disclosed |
| US-11376312-B2 | Composition and method for treating nucleic acid-related eye disease | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-07-05 | — | — | US | disclosed |
| EP-4004548-A1 | METHODS OF TREATING AND DIAGNOSING LUNG CANCER | Yeda Research and Development Co. Ltd (IL) | 2022-06-01 | — | — | EP | disclosed |
| US-20220155305-A1 | METHODS OF TREATING AND DIAGNOSING LUNG CANCER | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2022-05-19 | — | — | US | disclosed |