SCHEMBL29601585

SCHEMBL29601585

CCc1nnc(NC(=O)CN2CCOCC2)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.80
▸ POLB P06746 2/20 0.80
▸ KMT2A Q03164 2/20 0.63
▸ CA1 P00915 1/20 0.62
▸ CA2 P00918 1/20 0.62
▸ CA9 Q16790 1/20 0.62
▸ ALDH1A1 P00352 3/20 0.60
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ MEN1 O00255 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601968 0.90 KDM4E (0.98) KDM4EPOLBCA1CA2CA9
SCHEMBL29461389 0.84 KDM4E (0.67) KDM4EPOLBCA1CA2CA9
SCHEMBL14987175 0.84 KDM4E (0.74) KDM4EPOLBCA1CA2CA9
SCHEMBL22118520 0.77 CA1 (1.00) KDM4EPOLBCA1CA2CA9
SCHEMBL14192408 0.75 KAT8 (0.69) POLBKMT2AALDH1A1MEN1
SCHEMBL28804425 0.74 MAPT (0.64) KDM4EKMT2AALDH1A1L3MBTL1MEN1
SCHEMBL8832776 0.72 KAT8 (0.74) POLBKMT2AALDH1A1L3MBTL1MEN1
SCHEMBL8282186 0.72 KAT8 (0.65) POLBKMT2ACA1CA2ALDH1A1
SCHEMBL12354953 0.72 KAT8 (0.65) POLBKMT2AALDH1A1MEN1
SCHEMBL28759581 0.71 ATM (0.67) KDM4EPOLBALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12546775-B2 Peptides, reagents and methods for detecting food allergy AllerGenis, Inc. (US) 2026-02-10 — — US disclosed
US-20250388685-A1 METHODS FOR TREATING CHRONIC RHINOSINUSITIS WITHOUT NASAL POLYPS BY ADMINISTERING AN IL-4R ANTAGONIST SANOFI BIOTECHNOLOGY (FR) 2025-12-25 — — US disclosed
CN-118027033-A HDAC6 inhibitor, preparation method thereof and application thereof in anti-inflammatory and ulcerative colitis 四川大学 2024-05-14 — — CN disclosed
EP-4001920-A1 PEPTIDES AND METHODS FOR DETECTING FOOD ALLERGY AllerGenis, LLC (US) 2022-05-25 — — EP disclosed
US-20220155296-A1 Peptides, Reagents And Methods For Detecting Food Allergy AllerGenis, Inc. 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12546775-B2 Peptides, reagents and methods for detecting food allergy HLA-DRB1, IL33, SERPINA6 KDM4E 4464/4885POLB 3662/4885KMT2A 3029/4885
US-20250388685-A1 METHODS FOR TREATING CHRONIC RHINOSINUSITIS WITHOUT NASAL POLYPS BY ADMINISTERING AN IL-4R ANTAGONIST IL4, CCR4, IL1RN KDM4E 1295/4885POLB 2737/4885KMT2A 3005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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