SCHEMBL29601968

SCHEMBL29601968

CCCc1nnc(NC(=O)CN2CCOCC2)s1

nearest known ligand 0.98

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.98
▸ POLB P06746 1/20 0.98
▸ CA1 P00915 1/20 0.60
▸ CA2 P00918 1/20 0.60
▸ CA9 Q16790 1/20 0.60
▸ MAPT P10636 2/20 0.58
▸ ALDH1A1 P00352 3/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ CYP2D6 P10635 1/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ HSD17B10 Q99714 1/20 0.54
▸ CYP3A4 P08684 1/20 0.54
▸ CYP2C19 P33261 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601585 0.90 KDM4E (0.80) KDM4EPOLBCA1CA2CA9
SCHEMBL14987175 0.86 KDM4E (0.74) KDM4EPOLBCA1CA2CA9
SCHEMBL29461389 0.82 KDM4E (0.67) KDM4EPOLBCA1CA2CA9
SCHEMBL10800648 0.76 ALDH1A1 (0.72) KDM4EPOLBMAPTALDH1A1L3MBTL1
SCHEMBL22118520 0.75 CA1 (1.00) KDM4EPOLBCA1CA2CA9
SCHEMBL29359926 0.72 ALDH1A1 (0.65) KDM4EPOLBMAPTALDH1A1L3MBTL1
SCHEMBL29362473 0.72 ALDH1A1 (0.65) KDM4EPOLBMAPTALDH1A1L3MBTL1
SCHEMBL21368796 0.71 GLS (0.76) KDM4EPOLBALDH1A1MAPK1HSD17B10
SCHEMBL29423655 0.70 ALDH1A1 (0.63) KDM4EPOLBMAPTALDH1A1L3MBTL1
SCHEMBL10800392 0.69 RECQL (0.63) KDM4EMAPTALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115302-A1 TUMOR-SPECIFIC CLEAVABLE LINKERS XILIO DEV INC (US) 2026-04-30 — — US disclosed
US-12546775-B2 Peptides, reagents and methods for detecting food allergy AllerGenis, Inc. (US) 2026-02-10 — — US disclosed
US-20250388685-A1 METHODS FOR TREATING CHRONIC RHINOSINUSITIS WITHOUT NASAL POLYPS BY ADMINISTERING AN IL-4R ANTAGONIST SANOFI BIOTECHNOLOGY (FR) 2025-12-25 — — US disclosed
US-20250178822-A1 PREPACKAGED CHARGE OF EDIBLE MATERIAL POWDER, AND BEVERAGE PREPARATION SYSTEM USING SAID CHARGE CAFFE PASCUCCI TORREFAZIONE S P A (IT) 2025-06-05 — — US disclosed
CN-119930827-A Antibodies targeting PSCA and uses thereof 重庆精准生物技术有限公司 2025-05-06 — — CN disclosed
US-12280120-B2 Tumor-specific cleavable linkers Xilio Development, Inc. (US) 2025-04-22 — — US disclosed
EP-4489581-A1 PREPACKAGED CHARGE OF EDIBLE MATERIAL POWDER, AND BEVERAGE PREPARATION SYSTEM USING SAID CHARGE Caffé Pascucci Torrefazione S.P.A. (IT) 2025-01-15 — — EP disclosed
CN-118946272-A Pre-packaged sachet of edible material powder and beverage preparation system using the same 帕斯库奇咖啡烘焙股份有限公司 2024-11-12 — — CN disclosed
WO-2024076222-A1 COMPOSITION FOR REDUCING DROUGHT STRESS COMPRISING CULTURE SOLUTION OF AUREOBASIDIUM PULLULANS AK-10 STRAIN OR EXTRACT OF STRAIN CULTURE SOLUTION, AND METHOD FOR INDUCING DROUGHT STRESS REDUCTION 전남대학교산학협력단 2024-04-11 — — WO disclosed
WO-2023170594-A1 PREPACKAGED CHARGE OF EDIBLE MATERIAL POWDER, AND BEVERAGE PREPARATION SYSTEM USING SAID CHARGE. CAFFE' PASCUCCI TORREFAZIONE S.P.A. (IT) 2023-09-14 — — WO disclosed
US-20230159603-A1 MASKED IL-12 CYTOKINES AND THEIR CLEAVAGE PRODUCTS Xilio Development, Inc. 2023-05-25 — — US disclosed
US-20230151072-A1 MASKED IL-2 CYTOKINES AND THEIR CLEAVAGE PRODUCTS Xilio Development, Inc. 2023-05-18 — — US disclosed
US-20230072822-A1 TUMOR-SPECIFIC CLEAVABLE LINKERS Xilio Development, Inc. 2023-03-09 — — US disclosed
EP-4001920-A1 PEPTIDES AND METHODS FOR DETECTING FOOD ALLERGY AllerGenis, LLC (US) 2022-05-25 — — EP disclosed
US-20220155296-A1 Peptides, Reagents And Methods For Detecting Food Allergy AllerGenis, Inc. 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12546775-B2 Peptides, reagents and methods for detecting food allergy HLA-DRB1, IL33, SERPINA6 KDM4E 4464/4885POLB 3662/4885CA1 3981/4885
US-20250388685-A1 METHODS FOR TREATING CHRONIC RHINOSINUSITIS WITHOUT NASAL POLYPS BY ADMINISTERING AN IL-4R ANTAGONIST IL4, CCR4, IL1RN KDM4E 1295/4885POLB 2737/4885CA1 4633/4885
US-20260115302-A1 TUMOR-SPECIFIC CLEAVABLE LINKERS SPPL2B, SPPL2A, CTSL KDM4E 2739/4885POLB 3204/4885CA1 578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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