Bamipine

Bamipine

SCHEMBL29626

CN1CCC(N(Cc2ccccc2)c2ccccc2)CC1

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 3/20 0.66
DRD3 P35462 3/20 0.66
SLC6A2 P23975 2/20 0.66
SLC6A4 P31645 2/20 0.66
SLC6A3 Q01959 2/20 0.66
CHRM1 P11229 2/20 0.66
CHRM2 P08172 1/20 0.66
HTR1A P08908 1/20 0.66
ADRA2A P08913 1/20 0.66
DRD1 P21728 1/20 0.66
ADRA1A P35348 1/20 0.66
OPRM1 P35372 1/20 0.66
DRD2 P14416 3/20 0.57
PGR P06401 2/20 0.53
CCR5 P51681 3/20 0.50
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
PKM P14618 1/20 0.45
MEN1 O00255 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bamipine SCHEMBL4424873 0.98 KCNH2 (0.64) KCNH2DRD3SLC6A2SLC6A4SLC6A3
Bamipine SCHEMBL1649707 0.97 KCNH2 (0.63) KCNH2DRD3SLC6A2SLC6A4SLC6A3
Bamipine SCHEMBL3217102 0.93 OPRM1 (0.59) KCNH2DRD3SLC6A2SLC6A4SLC6A3
Bamipine SCHEMBL443443 0.89 KCNH2 (0.55) KCNH2DRD3SLC6A2SLC6A4SLC6A3
Bamipine SCHEMBL2968324 0.88 KCNH2 (0.54) KCNH2DRD3SLC6A2SLC6A4SLC6A3
SCHEMBL3542065 0.87 KCNH2 (0.56) KCNH2DRD3SLC6A2SLC6A4SLC6A3
SCHEMBL27703455 0.86 SLC6A2 (0.54) KCNH2DRD3SLC6A2SLC6A4SLC6A3
SCHEMBL12730900 0.81 KMT2A (0.58) KCNH2DRD3SLC6A2SLC6A4SLC6A3
SCHEMBL4492889 0.81 OPRD1 (0.61) OPRM1
SCHEMBL16307374 0.81 POLB (0.57) KCNH2DRD3SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1582 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4704971-A1 GAMMA STIMULATION AND NEUROMODULATOR COMBINATION THERAPY Cognito Therapeutics, Inc. (US) 2026-03-11 EP claimed
EP-4683527-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2026-01-28 EP claimed
US-12497381-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-12-16 US claimed
US-12478091-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-11-25 US claimed
US-12358889-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-07-15 US claimed
US-12358888-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-07-15 US claimed
WO-2025096261-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2025-05-08 WO claimed
WO-2025049141-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2025-03-06 WO claimed
US-20250049096-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2025-02-13 US claimed
US-20250041208-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2025-02-06 US claimed
US-20040171562-A1 Prodrugs activated by plasmin and their use in cancer chemotherapy E. R. SQUIBB & SONS, L.L.C. 2004-09-02 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
US-20020151541-A1 For treatment of respiratory tract diseases BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US claimed
EP-0704206-B1 Pharmaceutical composition MIKA PHARMA GES FUER DIE ENTWI (DE) 2002-09-04 EP claimed
WO-2002015700-A1 PRODRUGS ACTIVATED BY PLASMIN AND THEIR USE IN CANCER CHEMOTHERAPY COULTER PHARMACEUTICAL, INC. (US) 2002-02-28 WO claimed
EP-0713380-B1 FUNCTIONAL OXYGENATED COMPOSITION CONTAINING PHOSPHOLIPIDS AND FLUOROCARBON LANCASTER GROUP GMBH (DE) 2001-09-05 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
WO-1994008840-A1 MARINE ORGANISM REPELLENT FOR PROTECTING UNDERWATER OBJECTS FISCHER KENNETH J (US) 1994-04-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171562-A1 Prodrugs activated by plasmin and their use in cancer chemotherapy PLG, PLAT, DNPEP KCNH2 4842/4885DRD3 4090/4885SLC6A2 4542/4885
US-12358888-B2 Vaporizable alkaloid compositions and methods of use thereof SRM, SCLY, SMOX KCNH2 128/4885DRD3 556/4885SLC6A2 410/4885
US-12358889-B2 Vaporizable alkaloid compositions and methods of use thereof SRM, SCLY, SMOX KCNH2 128/4885DRD3 556/4885SLC6A2 410/4885
US-12497381-B2 Vaporizable alkaloid compositions and methods of use thereof CHRM5, NNMT, CHRM1 KCNH2 232/4885DRD3 532/4885SLC6A2 622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.