SCHEMBL29633016

SCHEMBL29633016

CCCCN(CCCC)CCc1c[nH]c2ccccc12

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 4/20 0.75
HTR1A P08908 3/20 0.75
HTR2A P28223 4/20 0.74
BCHE P06276 6/20 0.73
HTR2C P28335 2/20 0.65
HTR2B P41595 2/20 0.65
TRPM8 Q7Z2W7 1/20 0.62
TRPV1 Q8NER1 1/20 0.62
SLC6A4 P31645 2/20 0.61
HTR1D P28221 2/20 0.61
ADRA2A P08913 1/20 0.61
ADRA2B P18089 1/20 0.61
ADRA2C P18825 1/20 0.61
SLC6A2 P23975 1/20 0.61
HTR1E P28566 1/20 0.61
ADRA1A P35348 1/20 0.61
HRH1 P35367 1/20 0.61
ADRA1B P35368 1/20 0.61
DRD3 P35462 1/20 0.61
OPRK1 P41145 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20970873 1.00 HTR6 (0.75) HTR6HTR1AHTR2ABCHEHTR2C
SCHEMBL23996887 0.94 HTR1A (0.71) HTR6HTR1AHTR2ABCHEHTR2C
SCHEMBL1118996 0.91 HTR2A (0.88) HTR6HTR1AHTR2ABCHEHTR2C
SCHEMBL21073587 0.87 HTR2A (0.68) HTR6HTR1AHTR2ABCHEHTR2C
Diethyltryptamine SCHEMBL517713 0.86 HTR1A (1.00) HTR6HTR1AHTR2ABCHEHTR2C
SCHEMBL22027268 0.85 HTR2A (1.00) HTR6HTR1AHTR2ABCHEHTR2C
Diethyltryptamine SCHEMBL22462319 0.84 HTR1A (0.97) HTR6HTR1AHTR2AHTR2CHTR2B
Tryptamine SCHEMBL22800107 0.84 HTR2A (0.77) HTR6HTR1AHTR2ABCHEHTR2C
SCHEMBL266641 0.84 SLC6A4 (0.68) HTR6HTR1AHTR2AHTR2CHTR2B
Hydrochloric Acid SCHEMBL7869119 0.82 TRPM8 (0.72) HTR6HTR1AHTR2ABCHEHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME KULEON LLC (US) 2025-09-11 US disclosed
EP-4452986-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME Kuleon LLC (US) 2024-10-30 EP disclosed
US-20240342126-A1 HALLUCINOGEN-FATTY ACID COMBINATION MINDSET PHARMA INC. (CA) 2024-10-17 US disclosed
CN-118055766-A Magic and non-magic serotonin receptor agonist and its preparing process and usage 库莱恩有限责任公司 2024-05-17 CN disclosed
EP-4313007-A1 TRANSDERMAL SYSTEM, FORMULATION, AND METHOD FOR THE THERAPEUTIC ADMINISTRATION OF A PSYCHEDELIC AGENT Lyfe CHNG, LLC (US) 2024-02-07 EP disclosed
WO-2024020572-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PTSD NEW YORK STEM CELL FOUNDATION, INC. (US) 2024-01-25 WO disclosed
WO-2023225043-A1 TRICYCLIC AND TETRACYCLIC SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-11-23 WO disclosed
EP-4251181-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL CONDITIONS Wesana Health Inc. (US) 2023-10-04 EP disclosed
EP-4251139-A2 COMPOSITIONS AND METHODS FOR TREATING MIGRAINE Wesana Health Inc. (US) 2023-10-04 EP disclosed
WO-2023122135-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-06-29 WO disclosed
WO-2023023298-A1 HALLUCINOGENIC AND NON-HALLUCINOGENIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PSILOSTERICS, LLC (US) 2023-02-23 WO disclosed
WO-2022221072-A1 TRANSDERMAL SYSTEM, FORMULATION, AND METHOD FOR THE THERAPEUTIC ADMINISTRATION OF A PSYCHEDELIC AGENT MYCRODOSE THERAPEUTICS INC. (US) 2022-10-20 WO disclosed
WO-2022212789-A1 TRANSDERMAL SYSTEM, FORMULATION, AND METHOD FOR THE THERAPEUTIC ADMINISTRATION OF A PSYCHEDELIC AGENT MYCRODOSE THERAPEUTICS INC. (US) 2022-10-06 WO disclosed
WO-2022115798-A2 COMPOSITIONS AND METHODS FOR TREATING MIGRAINE WESANA HEALTH INC. (US) 2022-06-02 WO disclosed
WO-2022115796-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL CONDITIONS WESANA HEALTH INC. (US) 2022-06-02 WO disclosed
EP-3994458-A1 ARYLALKYLAMINE, PYRROLE, INDOLE AND OPIATE DERIVATIVE CONCENTRATION DETERMINATION METHOD AND TEST KIT USING SAID METHOD Blei, Felix (DE) 2022-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME HTR7, HTR2C, HTR1A HTR6 5/4885HTR1A 3/4885HTR2A 8/4885
US-20240342126-A1 HALLUCINOGEN-FATTY ACID COMBINATION FAAH, HTR5A, FAAH2 HTR6 7/4885HTR1A 10/4885HTR2A 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.