SCHEMBL29634757

SCHEMBL29634757

COC(=O)Oc1ccc([S+](C)C)cc1.CS(=O)(=O)[O-]

nearest known ligand 0.44

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MMP2 P08253 3/20 0.44
▸ MMP9 P14780 3/20 0.44
▸ MMP14 P50281 2/20 0.44
▸ KMT2A Q03164 4/20 0.39
▸ MAPT P10636 2/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ POLB P06746 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ HTT P42858 2/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ ELANE P08246 3/20 0.36
▸ MMP1 P03956 4/20 0.35
▸ MMP13 P45452 3/20 0.35
▸ CA1 P00915 1/20 0.34
▸ CA2 P00918 1/20 0.34
▸ MMP8 P22894 1/20 0.34
▸ ACR P10323 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6561499 0.90 KMT2A (0.46) MMP2MMP9MMP14KMT2AMAPT
Trifluoromethanesulfonic Acid SCHEMBL4168987 0.88 MMP2 (0.40) MMP2MMP9MMP14KMT2AMAPT
SCHEMBL31038957 0.87 MMP9 (0.42) MMP2MMP9MMP14MAPTPOLB
SCHEMBL9574184 0.81 ELANE (0.51) MMP2MMP9MMP14KMT2AMAPT
SCHEMBL10434604 0.80 KMT2A (0.50) KMT2AMAPTMEN1POLBPKM
SCHEMBL9619082 0.79 MAPT (0.40) MMP2MMP9MMP14KMT2AMAPT
SCHEMBL30313539 0.78 ELANE (0.48) KMT2AMAPTMEN1POLBPKM
SCHEMBL9646952 0.77 MAPT (0.54) KMT2AMAPTMEN1POLBPKM
SCHEMBL676909 0.76 KMT2A (0.58) MMP2MMP9MMP14KMT2AMAPT
SCHEMBL9356342 0.76 ELANE (0.53) KMT2AMAPTMEN1POLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114730132-B Curable resin composition, cured film, laminate, method for producing cured film, semiconductor device, and resin 富士胶片株式会社 2025-05-09 — — CN disclosed
CN-114761466-B Curable resin composition, cured film, laminate, method for producing cured film, semiconductor device, and resin 富士胶片株式会社 2024-12-10 — — CN disclosed
CN-114008527-B Curable resin composition, cured film, laminate, method for producing cured film, semiconductor device, and polyimide or polyimide precursor 富士胶片株式会社 2024-11-01 — — CN disclosed
CN-115867866-A Method for producing cured product, resin composition, developer, method for producing laminate, and method for producing semiconductor device 富士胶片株式会社 2023-03-28 — — CN disclosed
CN-115768832-A Resin composition, method for producing same, and method for producing composition for pattern formation 富士胶片株式会社 2023-03-07 — — CN disclosed
CN-115190891-A Curable resin composition, cured film, laminate, method for producing cured film, and semiconductor device 富士胶片株式会社 2022-10-14 — — CN disclosed
CN-115103871-A Resin composition, cured film, laminate, method for producing cured film, and semiconductor device 富士胶片株式会社 2022-09-23 — — CN disclosed
CN-115038755-A Curable resin composition, resin film, cured film, laminate, method for producing cured film, and semiconductor device 富士胶片株式会社 2022-09-09 — — CN disclosed
CN-114981360-A Curable resin composition, cured film, laminate, method for producing cured film, and semiconductor device 富士胶片株式会社 2022-08-30 — — CN disclosed
CN-114761466-A Curable resin composition, cured film, laminate, method for producing cured film, semiconductor device, and resin 富士胶片株式会社 2022-07-15 — — CN disclosed
CN-114730145-A Pattern forming method, photocurable resin composition, method for producing laminate, and method for producing electronic device 富士胶片株式会社 2022-07-08 — — CN disclosed
CN-114730132-A Curable resin composition, cured film, laminate, method for producing cured film, semiconductor device, and resin 富士胶片株式会社 2022-07-08 — — CN disclosed
CN-108700836-B Method for manufacturing laminate and method for manufacturing semiconductor device 富士胶片株式会社 2022-06-28 — — CN disclosed
CN-114514470-A Pattern forming method, photosensitive resin composition, method for manufacturing laminate, and method for manufacturing semiconductor device 富士胶片株式会社 2022-05-17 — — CN disclosed
Send feedback