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SCHEMBL29638142

SCHEMBL29638142

O=C(O)CO[C@H]1C(=O)c2c(O)cc(O)cc2O[C@@H]1c1ccc(O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CBS P35520 1/20 0.56
▸ MEN1 O00255 4/20 0.52
▸ KMT2A Q03164 4/20 0.52
▸ POLB P06746 2/20 0.52
▸ MAPT P10636 2/20 0.52
▸ THRB P10828 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ BLM P54132 1/20 0.52
▸ CYP3A4 P08684 3/20 0.49
▸ RECQL P46063 2/20 0.49
▸ CYP1A2 P05177 2/20 0.49
▸ ALOX12 P18054 2/20 0.49
▸ HSD17B10 Q99714 2/20 0.49
▸ SOST Q9BQB4 2/20 0.49
▸ KDM4E B2RXH2 1/20 0.49
▸ GAA P10253 1/20 0.49
▸ ALOX15 P16050 1/20 0.49
▸ NFKB1 P19838 1/20 0.49
▸ MAPK1 P28482 1/20 0.49
▸ HIF1A Q16665 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30291877 0.91 MAPT (0.62) CBSMEN1KMT2APOLBMAPT
SCHEMBL30915483 0.86 CYP2C9 (0.58) CBSMEN1KMT2APOLBMAPT
SCHEMBL30915482 0.86 CYP2C9 (0.58) CBSMEN1KMT2APOLBMAPT
SCHEMBL31527913 0.86 CBS (0.61) CBSMEN1KMT2APOLBMAPT
(+)-Taxifolin SCHEMBL29444269 0.84 CYP3A4 (0.68) MEN1KMT2APOLBMAPTCYP3A4
SCHEMBL30915471 0.83 ESR1 (0.59) CBSCYP19A1ESR1ESR2PSMB5
SCHEMBL25439511 0.82 CBS (0.68) CBSMEN1KMT2APOLBMAPT
SCHEMBL30576365 0.82 CBS (0.68) CBSMEN1KMT2APOLBMAPT
SCHEMBL25439509 0.82 CBS (0.68) CBSMEN1KMT2APOLBMAPT
SCHEMBL23085395 0.81 MEN1 (0.65) CBSMEN1KMT2APOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4627099-A2 PROCESS FOR MAKING FLAVANONE DERIVATIVES Firmenich SA (CH) 2025-10-08 — — EP claimed
WO-2024115469-A2 PROCESS FOR MAKING FLAVANONE DERIVATIVES FIRMENICH SA (CH) 2024-06-06 — — WO claimed
US-12635718-B2 Flavanone derivatives and their use as sweetness enhancers FIRMENICH SA (CH) 2026-05-26 — — US disclosed
EP-4725476-A2 COMPOSITIONS FOR REDUCING SALTY TASTE AND USES THEREOF Firmenich SA (CH) 2026-04-15 — — EP disclosed
EP-4096714-B1 COMPOSITIONS FOR REDUCING SALTY TASTE AND USES THEREOF FIRMENICH & CIE (CH) 2026-01-28 — — EP disclosed
US-20250387310-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2025-12-25 — — US disclosed
EP-4627099-A2 PROCESS FOR MAKING FLAVANONE DERIVATIVES Firmenich SA (CH) 2025-10-08 — — EP disclosed
EP-4627099-A2 PROCESS FOR MAKING FLAVANONE DERIVATIVES Firmenich SA (CH) 2025-10-08 — — EP disclosed
WO-2025202256-A1 COOLING COMPOSITION FIRMENICH SA (CH) 2025-10-02 — — WO disclosed
US-20250275560-A1 PROCESS OF MAKING GINGEROL COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS FIRMENICH SA (CH) 2025-09-04 — — US disclosed
EP-4583718-A1 FLAVONOID COMPOSITIONS AND USES THEREOF Firmenich SA (CH) 2025-07-16 — — EP disclosed
EP-4055006-A1 AMINO ACID DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS Firmenich SA (CH) 2022-09-14 — — EP disclosed
US-20220273011-A1 GINGEROL COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS FIRMENICH SA (CH) 2022-09-01 — — US disclosed
US-20220273012-A1 FLAVANONE DERIVATIVES AND THEIR USE AS SWEETNESS ENHANCERS FIRMENICH SA (CH) 2022-09-01 — — US disclosed
EP-4048086-A1 11-OXO-CUCURBITANES AND THEIR USE AS FLAVOR MODIFIERS Firmenich SA (CH) 2022-08-31 — — EP disclosed
WO-2022155054-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2022-07-21 — — WO disclosed
EP-4025071-A1 FLAVANONE DERIVATIVES AND THEIR USE AS SWEETNESS ENHANCERS Firmenich SA (CH) 2022-07-13 — — EP disclosed
WO-2022136288-A1 USES OF FAT BLENDS AND EMULSIONS THEREOF FIRMENICH SA (CH) 2022-06-30 — — WO disclosed
US-20220167642-A1 FAT BLENDS, EMULSIONS THEREOF, AND RELATED USES FIRMENICH SA (CH) 2022-06-02 — — US disclosed
WO-2022090218-A1 CONJUGATED DIYNES AND THEIR USE AS FLAVOR MODIFIERS FIRMENICH SA (CH) 2022-05-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250275560-A1 PROCESS OF MAKING GINGEROL COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS GMPS, UMPS, IMPDH1 CBS 605/4885MEN1 1573/4885KMT2A 3440/4885
US-20220273012-A1 FLAVANONE DERIVATIVES AND THEIR USE AS SWEETNESS ENHANCERS GCK, FN3K, GCKR CBS 2312/4885MEN1 3093/4885KMT2A 1652/4885
US-12635718-B2 Flavanone derivatives and their use as sweetness enhancers TAS2R10, TAS2R20, TAS2R7 CBS 2614/4885MEN1 1914/4885KMT2A 3381/4885
US-20250387310-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT TAS2R30, TAS2R1, TAS2R20 CBS 771/4885MEN1 2514/4885KMT2A 2006/4885
US-20220273011-A1 GINGEROL COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS GMPS, IMPDH1, IMPDH2 CBS 845/4885MEN1 1485/4885KMT2A 2567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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