SCHEMBL29641047

SCHEMBL29641047

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 12/20 0.54
▸ NPY1R P25929 7/20 0.54
▸ NPY2R P49146 6/20 0.54
▸ NPY5R Q15761 6/20 0.54
▸ EIF4E P06730 1/20 0.51
▸ EIF4EBP1 Q13541 1/20 0.51
▸ KEAP1 Q14145 1/20 0.50
▸ TUBB4A P04350 1/20 0.49
▸ TUBB P07437 1/20 0.49
▸ TUBA3C P0DPH7 1/20 0.49
▸ TUBA1B P68363 1/20 0.49
▸ TUBA4A P68366 1/20 0.49
▸ TUBB4B P68371 1/20 0.49
▸ TUBB3 Q13509 1/20 0.49
▸ TUBB2A Q13885 1/20 0.49
▸ TUBB8 Q3ZCM7 1/20 0.49
▸ TUBA3E Q6PEY2 1/20 0.49
▸ TUBA1A Q71U36 1/20 0.49
▸ TUBA1C Q9BQE3 1/20 0.49
▸ TUBB6 Q9BUF5 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30059086 0.95 GLP1R (0.51) NPY4RNPY1RNPY2RNPY5RTUBB4A
SCHEMBL29461974 0.92 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RTUBB4A
SCHEMBL29641002 0.92 NPY4R (0.54) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL29641071 0.92 IL23R (0.57) NPY2RTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL29641105 0.92 IL23R (0.57) NPY2RTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL29461983 0.91 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30592738 0.91 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30589456 0.91 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30974032 0.89 NPY4R (0.54) NPY4RNPY1RNPY2RNPY5RTUBB4A
SCHEMBL30589457 0.89 C5AR1 (0.45) NPY4RNPY1RNPY2RNPY5RTUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4711005-A2 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH Stealth BioTherapeutics Inc. (US) 2026-03-18 — — EP disclosed
US-20260061023-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF BARTH SYNDROME STEALTH BIOTHERAPEUTICS INC. (US) 2026-03-05 — — US disclosed
US-20250319152-A1 METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING STEALTH BIOTHERAPEUTICS INC. (US) 2025-10-16 — — US disclosed
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TUFTS MEDICAL CENTER, INC. 2025-09-04 — — US disclosed
US-20250263433-A1 METHODS FOR REDUCING CD36 EXPRESSION CORNELL RESEARCH FOUNDATION, INC. (US) 2025-08-21 — — US disclosed
US-20250255929-A1 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH STEALTH BIOTHERAPEUTICS INC. (US) 2025-08-14 — — US disclosed
EP-4596049-A2 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2025-08-06 — — EP disclosed
US-12337023-B2 Methods and compositions for the prevention and treatment of disease STEALTH BIOTHERAPEUTICS INC. (US) 2025-06-24 — — US disclosed
US-20250161401-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2025-05-22 — — US disclosed
EP-4302829-B1 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION STEALTH BIOTHERAPEUTICS INC (US) 2025-05-21 — — EP disclosed
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2023-04-06 — — US disclosed
US-20230043587-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DISEASE STEALTH BIOTHERAPEUTICS INC. (US) 2023-02-09 — — US disclosed
EP-3513800-B1 AROMATIC-CATIONIC PEPTIDE FOR USE IN THE TREATMENT OF ANTIPHOSPHOLIPID SYNDROME UNIV CORNELL (US) 2022-12-07 — — EP disclosed
EP-4085920-A1 METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY Stealth BioTherapeutics Inc. (US) 2022-11-09 — — EP disclosed
US-20220296672-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT NEUROPATHY STEALTH BIOTHERAPEUTICS INC. (US) 2022-09-22 — — US disclosed
US-11420998-B2 Aromatic-cationic peptides and methods for using same STEALTH BIOTHERAPEUTICS INC. (US) 2022-08-23 — — US disclosed
US-11376304-B2 Methods and compositions for the prevention and treatment of disease STEALTH BIOTHERAPEUTICS INC. (US) 2022-07-05 — — US disclosed
US-11366104-B2 Methods of identifying and monitoring mitochondrial dysfunction using monocyte screening STEALTH BIOTHERAPEUTICS INC. (US) 2022-06-21 — — US disclosed
EP-4005582-A1 TREATMENT OF LEFT VENTRICULAR REMODELING Stealth BioTherapeutics Inc. (US) 2022-06-01 — — EP disclosed
EP-4000690-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES Stealth BioTherapeutics Inc. (US) 2022-05-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230043587-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DISEASE COL2A1, ALPI, COL14A1 NPY4R 223/4885NPY1R 735/4885NPY2R 820/4885
US-20260061023-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF BARTH SYNDROME ARG2, ARGLU1, BCAT1 NPY4R 2600/4885NPY1R 872/4885NPY2R 1761/4885
US-20250255929-A1 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH TNNI3, TNNT2, FABP3 NPY4R 2454/4885NPY1R 1553/4885NPY2R 2489/4885
US-12337023-B2 Methods and compositions for the prevention and treatment of disease COL2A1, ALPI, COL14A1 NPY4R 223/4885NPY1R 735/4885NPY2R 820/4885
US-20220296672-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT NEUROPATHY NGF, GAP43, PRPH NPY4R 520/4885NPY1R 328/4885NPY2R 395/4885
US-20250161401-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY MTPN, UTRN, SMN1; SMN2 NPY4R 2905/4885NPY1R 2251/4885NPY2R 2584/4885
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY MTPN, UTRN, SMN1; SMN2 NPY4R 2905/4885NPY1R 2251/4885NPY2R 2584/4885
US-20250319152-A1 METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING ARG2, TNNT2, MYLK2 NPY4R 700/4885NPY1R 913/4885NPY2R 313/4885
US-11420998-B2 Aromatic-cationic peptides and methods for using same ARG2, ARGLU1, ARG1 NPY4R 824/4885NPY1R 523/4885NPY2R 730/4885
US-11376304-B2 Methods and compositions for the prevention and treatment of disease COL2A1, ALPI, COL14A1 NPY4R 223/4885NPY1R 735/4885NPY2R 820/4885
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TNNI3, TNNT2, MB NPY4R 4783/4885NPY1R 4818/4885NPY2R 4654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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