Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 11/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | TLR4 | O00206 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | TYMS | P04818 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | FOLR2 | P14207 | 1/20 | 0.67 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | GART | P22102 | 1/20 | 0.67 |
| ▸ | APEX1 | P27695 | 1/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221621 | 1.00 | DHFR (0.71) | DHFRKDM4ETLR4MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1230259 | 0.99 | DHFR (0.70) | DHFRKDM4ETLR4MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3171572 | 0.98 | DHFR (0.69) | DHFRKDM4ETLR4MEN1ALDH1A1 | |
| SCHEMBL30110296 | 0.92 | DHFR (0.62) | DHFRKDM4ETLR4MEN1ALDH1A1 | |
| SCHEMBL11913611 | 0.91 | DHFR (0.71) | DHFRKDM4ETLR4MEN1ALDH1A1 | |
| SCHEMBL13985918 | 0.91 | DHFR (0.71) | DHFRKDM4ETLR4MEN1ALDH1A1 | |
| SCHEMBL13529957 | 0.91 | DHFR (0.60) | DHFRKDM4ETLR4MEN1ALDH1A1 | |
| SCHEMBL10379252 | 0.90 | DHFR (0.59) | DHFRKDM4ETLR4MEN1ALDH1A1 | |
| SCHEMBL14753789 | 0.89 | DHFR (0.66) | DHFRKDM4ETLR4MEN1ALDH1A1 | |
| SCHEMBL22201137 | 0.88 | HDAC4 (0.70) | DHFRKDM4ETLR4MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115561355-B | Method for detecting neutralizing antibody of carboxypeptidase G2 and detection system based on LC-MS/MS | 重庆迪纳利医药科技有限责任公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117607306-A | Method and kit for simultaneously detecting methotrexate and various metabolites thereof | 长沙都正生物科技股份有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-115561355-A | Method for detecting neutralizing antibody of carboxypeptidase G2 and LC-MS/MS-based detection system | 重庆迪纳利医药科技有限责任公司 | 2023-01-03 | — | — | CN | claimed |
| EP-3630994-B1 | SENSORS, METHODS AND KITS FOR DETECTING NADPH BASED ON RESONANCE ENERGY TRANSFER. | MAX PLANCK GESELLSCHAFT (DE) | 2022-08-10 | — | — | EP | claimed |
| US-20260104979-A1 | PLATFORM ASSISTED OS/WORKLOAD AGNOSTIC OPTIMAL MEMORY TIERING ACROSS NODES FOR DISTRIBUTED APPLICATIONS | DELL PRODUCTS LP (US) | 2026-04-16 | — | — | US | disclosed |
| US-20260000771-A1 | PSMA-TARGETING LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME | TARGIMMUNE THERAPEUTICS AG (CH) | 2026-01-01 | — | — | US | disclosed |
| US-20260000700-A1 | TARGETED LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME | TARGIMMUNE THERAPEUTICS AG (CH) | 2026-01-01 | — | — | US | disclosed |
| WO-2025238236-A1 | POLYPLEXES OF NUCLEIC ACIDS AND TARGETED CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL | TARGIMMUNE THERAPEUTICS AG (CH) | 2025-11-20 | — | — | WO | disclosed |
| EP-4615511-A1 | TARGETED LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME | TargImmune Therapeutics AG (CH) | 2025-09-17 | — | — | EP | disclosed |
| EP-4615510-A1 | POLYPLEXES OF NUCLEIC ACIDS AND TARGETED CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL | TargImmune Therapeutics AG (CH) | 2025-09-17 | — | — | EP | disclosed |
| EP-4615509-A1 | PSMA-TARGETING LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME | TargImmune Therapeutics AG (CH) | 2025-09-17 | — | — | EP | disclosed |
| US-20250255991-A1 | SYNTHESIS AND COMPOSITION OF PHOTODYNAMIC THERAPEUTIC AGENTS FOR THE TARGETED TREATMENT OF CANCER | ON TARGET LABORATORIES INC (US) | 2025-08-14 | — | — | US | disclosed |
| CN-116209476-A | Antifolate linker-drug and antibody-drug conjugates | 拜奥迪斯私人有限公司 | 2023-06-02 | — | — | CN | disclosed |
| WO-2023079142-A2 | TARGETED LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME | TARGIMMUNE THERAPEUTICS AG (CH) | 2023-05-11 | — | — | WO | disclosed |
| CN-115561355-A | Method for detecting neutralizing antibody of carboxypeptidase G2 and LC-MS/MS-based detection system | 重庆迪纳利医药科技有限责任公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-111748505-B | Genetically engineered bacterium for expressing carboxypeptidase G2 and preparation method and application thereof | 上海医药工业研究院 | 2022-12-30 | — | — | CN | disclosed |
| US-20220241429-A1 | Antifolate-Carrying Nanoparticles and Their Use in Medicine | MIDATECH LTD (GB) | 2022-08-04 | — | — | US | disclosed |
| CN-114810343-A | Misfire detection apparatus for internal combustion engine | 丰田自动车株式会社 | 2022-07-29 | — | — | CN | disclosed |
| CN-114629388-A | LC resonance suppression method based on virtual admittance remodeling | 哈尔滨工业大学 | 2022-06-14 | — | — | CN | disclosed |
| US-20220160712-A1 | METHODS OF TREATING RHEUMATOID ARTHRITIS AND FOR PREDICTING THE RESPONSE TO METHOTREXATE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250255991-A1 | SYNTHESIS AND COMPOSITION OF PHOTODYNAMIC THERAPEUTIC AGENTS FOR THE TARGETED TREATMENT OF CANCER | ERAL1, TK2, PYCR1 | DHFR 148/4885KDM4E 4669/4885TLR4 639/4885 |
| US-20260104979-A1 | PLATFORM ASSISTED OS/WORKLOAD AGNOSTIC OPTIMAL MEMORY TIERING ACROSS NODES FOR DISTRIBUTED APPLICATIONS | NPM1, DAPK1, APP | DHFR 1370/4885KDM4E 4141/4885TLR4 2591/4885 |
| US-20260000771-A1 | PSMA-TARGETING LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME | PSMA1, PSMA3, PSMA2 | DHFR 371/4885KDM4E 3243/4885TLR4 2860/4885 |
| US-20260000700-A1 | TARGETED LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME | CTDSP1, POLM, MCTS1 | DHFR 576/4885KDM4E 4503/4885TLR4 1793/4885 |
| US-20220241429-A1 | Antifolate-Carrying Nanoparticles and Their Use in Medicine | FOLR1, FOLR2, SLC19A1 | DHFR 4/4885KDM4E 4710/4885TLR4 2854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.