Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.47 |
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.49 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.49 |
| ▸ | TST | Q16762 | 2/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16446112 | 1.00 | NR4A1 (0.61) | NR4A1HSPD1HSPE1TSTENPP2 | |
| SCHEMBL8508834 | 1.00 | NR4A1 (0.61) | NR4A1HSPD1HSPE1TSTENPP2 | |
| SCHEMBL31709341 | 1.00 | NR4A1 (0.61) | NR4A1HSPD1HSPE1TSTENPP2 | |
| Water SCHEMBL12275144 | 0.98 | NR4A1 (0.60) | NR4A1HSPD1HSPE1TSTENPP2 | |
| Lithium Ion SCHEMBL155096 | 0.97 | NR4A1 (0.61) | NR4A1HSPD1HSPE1TSTENPP2 | |
| SCHEMBL1459623 | 0.93 | NR4A1 (0.57) | NR4A1HSPD1HSPE1TSTENPP2 | |
| SCHEMBL30683823 | 0.93 | NR4A1 (0.57) | NR4A1HSPD1HSPE1TSTENPP2 | |
| SCHEMBL29435294 | 0.93 | NR4A1 (0.57) | NR4A1HSPD1HSPE1TSTENPP2 | |
| SCHEMBL29608931 | 0.81 | AURKB (0.64) | NR4A1AURKAAURKBTHRBCYP3A4 | |
| SCHEMBL156055 | 0.81 | AURKB (0.64) | NR4A1AURKAAURKBTHRBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025099313-A1 | REDUCING BACKGROUND FLUORESCENCE IN SINGLE MOLECULE FLUORESCENCE IN SITU HYBRIDIZATION APPLICATIONS | RESOLVE BIOSCIENCES GMBH (DE) | 2025-05-15 | — | — | WO | disclosed |
| CN-118338916-A | Multifunctional compounds for use in medical imaging and therapy | 安特络手术解决方案公司 | 2024-07-12 | — | — | CN | disclosed |
| WO-2022095057-A1 | PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 深圳先进技术研究院 | 2022-05-12 | — | — | WO | disclosed |