Isracidin

Isracidin

SCHEMBL29668326

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)O)C(C)C

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 10/20 0.70
▸ NPY4R P50391 8/20 0.70
▸ NPY5R Q15761 8/20 0.70
▸ NPY1R P25929 8/20 0.70
▸ TFPI P10646 4/20 0.69
▸ PTH1R Q03431 4/20 0.63
▸ CXCR4 P61073 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29407563 0.89 PTH1R (0.69) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30495701 0.87 NPY2R (0.64) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29776068 0.87 TFPI (0.65) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29356071 0.87 RAMP3 (0.65) NPY2RNPY4RNPY5RNPY1R
SCHEMBL29352518 0.87 RAMP3 (0.65) NPY2RNPY4RNPY5RNPY1R
Sor-C13 SCHEMBL29926670 0.87 TFPI (0.67) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL31183026 0.87 NPY2R (0.64) NPY2RNPY4RNPY5RNPY1RTFPI
Dirucotide SCHEMBL29359894 0.86 AGTR1 (0.64) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL4331434 0.86 NPY2R (0.75) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL31544752 0.86 TFPI (0.60) NPY2RNPY4RNPY5RNPY1RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119639851-A Preparation method and application of milk-derived immunomodulatory peptide 大连工业大学 2025-03-18 — — CN claimed
US-20240099984-A1 A BIODISSOLVABLE FILM FOR LOCALIZED AND EFFICIENT TREATMENT OF VULVODYNIA THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2024-03-28 — — US claimed
US-12582140-B2 Method of preparing casein hydrolysate ARLA FOODS AMBA (DK) 2026-03-24 — — US disclosed
US-20250134895-A1 METHODS AND COMPOSITIONS FOR TREATING ALPHA-SYNUCLEIN-MEDIATED NEURODEGENERATION UNIVERSITY HEALTH NETWORK (CA) 2025-05-01 — — US disclosed
US-20250109143-A1 KLF2 INDUCING DEUTERATED COMPOUNDS AND USES THEREOF RIPARIAN PHARMACEUTICALS, INC. (US) 2025-04-03 — — US disclosed
CN-119639851-A Preparation method and application of milk-derived immunomodulatory peptide 大连工业大学 2025-03-18 — — CN disclosed
WO-2025032440-A1 KLF2 INDUCING COMPOUNDS AND USES THEREOF PFIZER INC. (US) 2025-02-13 — — WO disclosed
EP-4470382-A1 PLANT EXTRACT AND METHODS COMPRISING THEREOF FUNDACION UNIVERSITARIA SAN ANTONIO (UCAM) (ES) 2024-12-04 — — EP disclosed
US-20240264173-A1 METHOD OF PROGNOSIS PLAQUETEC LTD. (GB) 2024-08-08 — — US disclosed
US-20240099984-A1 A BIODISSOLVABLE FILM FOR LOCALIZED AND EFFICIENT TREATMENT OF VULVODYNIA THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2024-03-28 — — US disclosed
EP-4341698-A1 METHOD OF PROGNOSIS Plaquetec Ltd (GB) 2024-03-27 — — EP disclosed
US-20230276827-A1 METHOD OF PREPARING CASEIN HYDROLYSATE ARLA FOODS AMBA (DK) 2023-09-07 — — US disclosed
US-20230218659-A1 Selenium-Based Compositions and Therapeutic Methods HESS PHARMACEUTICALS, INC. (US) 2023-07-13 — — US disclosed
EP-2938328-B1 MONOLITHIC PHARMACEUTICAL FORM FOR MODIFIED RELEASE OF AN ACTIVE INGREDIENT COMBINATION HENNIG ARZNEIMITTEL GMBH&CO KG (DE) 2023-07-05 — — EP disclosed
WO-2023019351-A1 METHODS AND COMPOSITIONS FOR TREATING ALPHA-SYNUCLEIN-MEDIATED NEURODEGENERATION UNIVERSITY HEALTH NETWORK (CA) 2023-02-23 — — WO disclosed
US-20230044257-A1 COMPOSITIONS AND METHODS FOR ENHANCED UPTAKE OF ACTIVE INGREDIENTS FOR ANIMAL HEALTH AND NUTRITION AGROSPHERES, INC. 2023-02-09 — — US disclosed
WO-2022243703-A1 METHOD OF PROGNOSIS PLAQUETEC LTD (GB) 2022-11-24 — — WO disclosed
EP-4061802-A2 COMPOSITIONS AND METHODS FOR ENHANCED UPTAKE OF ACTIVE INGREDIENTS FOR ANIMAL HEALTH AND NUTRITION Agrospheres, Inc. (US) 2022-09-28 — — EP disclosed
US-11346797-B2 System and method for monitoring cardiomyocyte beating, viability, morphology and electrophysiological properties AGILENT TECHNOLOGIES, INC. (US) 2022-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250134895-A1 METHODS AND COMPOSITIONS FOR TREATING ALPHA-SYNUCLEIN-MEDIATED NEURODEGENERATION SNCA, SAMHD1, MAPT NPY2R 4666/4885NPY4R 4411/4885NPY5R 3804/4885
US-20250109143-A1 KLF2 INDUCING DEUTERATED COMPOUNDS AND USES THEREOF KLF5, KLF10, SREBF2 NPY2R 2683/4885NPY4R 3565/4885NPY5R 3564/4885
US-12582140-B2 Method of preparing casein hydrolysate MCRS1, CPN1, CTRL NPY2R 1371/4885NPY4R 1417/4885NPY5R 1266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback