Dirucotide

Dirucotide

SCHEMBL29359894

CC[C@H](C)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)O)[C@@H](C)O)[C@@H](C)O)C(C)C

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ AGTR1 P30556 1/20 0.64
▸ AGTR2 P50052 1/20 0.64
▸ NPY2R P49146 8/20 0.62
▸ NPY4R P50391 8/20 0.62
▸ NPY5R Q15761 8/20 0.62
▸ NPY1R P25929 6/20 0.62
▸ TFPI P10646 6/20 0.59
▸ REN P00797 3/20 0.58
▸ CXCR4 P61073 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Angiotensin Ii SCHEMBL513519 0.87 AGTR2 (0.82) AGTR1AGTR2NPY2RNPY4RNPY5R
Angiotensin Ii SCHEMBL2566771 0.86 AGTR2 (0.84) AGTR1AGTR2REN
Angiotensin Ii SCHEMBL1189 0.86 AGTR2 (0.84) AGTR1AGTR2REN
Angiotensin Ii SCHEMBL13232382 0.86 AGTR2 (0.84) AGTR1AGTR2REN
Angiotensin Ii SCHEMBL14990505 0.86 AGTR2 (0.83) AGTR1AGTR2REN
Angiotensin Ii SCHEMBL21267957 0.86 AGTR2 (0.83) AGTR1AGTR2REN
Angiotensin Ii SCHEMBL3465991 0.86 AGTR2 (0.83) AGTR1AGTR2REN
SCHEMBL30950135 0.86 CALCR (0.57) NPY2RNPY4RNPY5RNPY1R
Isracidin SCHEMBL29668326 0.86 NPY2R (0.70) NPY2RNPY4RNPY5RNPY1RTFPI
Angiotensin Ii SCHEMBL3044639 0.86 AGTR2 (0.81) AGTR1AGTR2REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250032503-A1 USE OF APREPITANT FOR TREATING ALZHEIMER'S DISEASE HOTH THERAPEUTICS, INC. 2025-01-30 — — US claimed
WO-2023196958-A2 TUMOR AND CANCER TARGETING COMPOUNDS ONCOLINX PHARMACEUTICALS (US) 2023-10-12 — — WO claimed
US-20230082167-A1 NOVEL TRICYCLIC COMPOUNDS ABBVIE INC (US) 2023-03-16 — — US claimed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
EP-4342543-B1 TERT-BUTYL 2-(4-PHENYL-6H-THIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A] [1,4]DIAZEPIN-6-YL) ACETATE DERIVATIVES AS BROMODOMAIN BRD4 INHIBITORS FOR TREATING CANCER HOFFMANN LA ROCHE (CH) 2026-04-29 — — EP disclosed
US-12612631-B2 Small RNA medicament for prevention and treatment of inflammation-related diseases and combination thereof BEIJING BAISHIHEKANG PHARMACEUTICAL TECHNOLOGY (BSJPHARMA) CO., LTD (CN) 2026-04-28 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
EP-4168399-B1 COMPOUNDS AND THEIR USES AS MIF INHIBITORS NANJING IMMUNOPHAGE BIOMEDICAL CO LTD (CN) 2026-04-01 — — EP disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
US-12569556-B2 Aluminum based adjuvants for tolerogenic vaccination EAST CAROLINA UNIVERSITY (US) 2026-03-10 — — US disclosed
CN-114126619-A Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-03-01 — — CN disclosed
EP-3464270-B1 HETEROCYCLIC INHIBITORS OF CBP/EP300 AND THEIR USE IN THE TREATMENT OF CANCER GENENTECH INC (US) 2022-02-23 — — EP disclosed
US-20220049275-A1 SSI CELLS WITH PREDICTABLE AND STABLE TRANSGENE EXPRESSION AND METHODS OF FORMATION LONZA AG (CH) 2022-02-17 — — US disclosed
US-11247989-B2 Therapeutic compounds and uses thereof GENENTECH, INC. (US) 2022-02-15 — — US disclosed
US-20220042064-A1 CARBON-SOURCE REGULATED PROTEIN PRODUCTION IN A RECOMBINANT HOST CELL LONZA LTD (CH) 2022-02-10 — — US disclosed
EP-3947695-A1 MUT- METHYLOTROPHIC YEAST Universität für Bodenkultur Wien (AT) 2022-02-09 — — EP disclosed
CN-114026239-A MUT-methanol nutritional yeast 维也纳自然资源与生命科学大学 2022-02-08 — — CN disclosed
US-11236520-B2 Customizable facility LONZA LTD (CH) 2022-02-01 — — US disclosed
EP-3942014-A1 CONTINUOUS BLADE IMPELLER Lonza Ltd. (CH) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS AGTR1 580/4885AGTR2 617/4885NPY2R 111/4885
US-12612631-B2 Small RNA medicament for prevention and treatment of inflammation-related diseases and combination thereof EIF2AK2, IL1A, IRF3 AGTR1 1139/4885AGTR2 1628/4885NPY2R 4355/4885
US-11247989-B2 Therapeutic compounds and uses thereof EP300, HDAC1, CREBBP AGTR1 669/4885AGTR2 839/4885NPY2R 772/4885
US-20250032503-A1 USE OF APREPITANT FOR TREATING ALZHEIMER'S DISEASE TACR1, ACHE, TACR2 AGTR1 60/4885AGTR2 95/4885NPY2R 84/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 AGTR1 312/4885AGTR2 526/4885NPY2R 150/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 AGTR1 883/4885AGTR2 1608/4885NPY2R 1754/4885
US-20230082167-A1 NOVEL TRICYCLIC COMPOUNDS CYP11B2, CYP11B1, ABCB1 AGTR1 521/4885AGTR2 595/4885NPY2R 1961/4885
US-12569556-B2 Aluminum based adjuvants for tolerogenic vaccination IFNG, MYH2, MYH10 AGTR1 1843/4885AGTR2 2294/4885NPY2R 4027/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT AGTR1 539/4885AGTR2 1134/4885NPY2R 791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback