SCHEMBL29407563

SCHEMBL29407563

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CO)C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)O)C(C)C

nearest known ligand 0.69

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PTH1R Q03431 7/20 0.69
▸ NPY2R P49146 7/20 0.68
▸ NPY4R P50391 7/20 0.68
▸ NPY5R Q15761 7/20 0.68
▸ NPY1R P25929 5/20 0.68
▸ CXCR4 P61073 1/20 0.68
▸ TFPI P10646 4/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29895442 0.93 CALCR (0.73) PTH1R
SCHEMBL6437853 0.93 CALCR (0.73) PTH1R
SCHEMBL31139067 0.91 CALCR (0.62) PTH1RNPY2RNPY4RNPY5RNPY1R
SCHEMBL29939518 0.90 CALCR (0.58) PTH1RNPY2RNPY4RNPY5RNPY1R
SCHEMBL29977603 0.90 NPY2R (0.69) PTH1RNPY2RNPY4RNPY5RNPY1R
Isracidin SCHEMBL29668326 0.89 NPY2R (0.70) PTH1RNPY2RNPY4RNPY5RNPY1R
Scyllatoxin SCHEMBL29388554 0.89 PTH1R (0.74) PTH1R
SCHEMBL30887555 0.87 CALCR (0.66) NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL9979655 0.87 NPY2R (0.69) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL15669203 0.86 NPY2R (0.74) NPY2RNPY4RNPY5RNPY1RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096779-A2 METHODS OF TREATMENT WITH A MYOSIN INHIBITOR USING PROTEIN LEVELS BRISTOL MYERS SQUIBB COMPANY (US) 2025-05-08 — — WO claimed
CN-111527410-B Standard for BNP measurement 盐野义制药株式会社 2024-09-10 — — CN claimed
CN-116814608-A Kit for extracting staphylococcus aureus DNA by magnetic bead method and extraction method thereof 山东博弘基因科技有限公司 2023-09-29 — — CN claimed
CN-110339346-B External skin preparation composition IGISU株式会社 2023-06-27 — — CN claimed
EP-3734287-B1 REFERENCE STANDARD FOR BNP MEASUREMENT SHIONOGI & CO (JP) 2023-05-17 — — EP claimed
US-11561230-B2 Reference standard for BNP measurement SHIONOGI & CO., LTD. (JP) 2023-01-24 — — US claimed
US-12601746-B2 Biomarkers of renal injury UNIVERSITY OF PITTSBURGH- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2026-04-14 — — US disclosed
US-12590131-B2 Antimicrobial peptides with alpha-core helices LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER (US) 2026-03-31 — — US disclosed
US-12590975-B2 Methods and compositions for diagnosis and prognosis of renal injury and renal failure BIOMERIEUX, INC. (US) 2026-03-31 — — US disclosed
US-12560616-B2 Methods and compositions for diagnosis and prognosis of renal injury and renal failure BIOMERIEUX, INC. (US) 2026-02-24 — — US disclosed
US-20250283153-A1 MULTIPLEX METHODS OF DETECTING MOLECULES USING NANOPORES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-09-11 — — US disclosed
EP-3621632-B1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) 2025-08-13 — — EP disclosed
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2025-06-05 — — US disclosed
US-20220099687-A1 POLYCLONAL-MONOCLONAL ELISA ASSAY FOR DETECTING N-TERMINUS PRO-BNP NEXUS DX INC (US) 2022-03-31 — — US disclosed
EP-3974836-A1 METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE Astute Medical, Inc. (US) 2022-03-30 — — EP disclosed
CN-114207436-A Methods for assessing and treating renal injury based on C-C motif chemokine ligand 14 measurements 机敏医药股份有限公司 2022-03-18 — — CN disclosed
CN-111848776-B Polyethylene glycol modified rhBNP and preparation method thereof 江苏璟泽生物医药有限公司 2022-03-18 — — CN disclosed
EP-3968022-A1 METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE Astute Medical, Inc. (US) 2022-03-16 — — EP disclosed
US-11262363-B2 Methods and compositions for diagnosis and prognosis of renal injury and renal failure ASTUTE MEDICAL, INC. (US) 2022-03-01 — — US disclosed
CN-114088950-A Methods and compositions for evaluating and treating renal injury and renal failure based on C-C motif chemokine ligand 14 measurements 机敏医药股份有限公司 2022-02-25 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12560616-B2 Methods and compositions for diagnosis and prognosis of renal injury and renal failure CHI3L1, CHI3L2, CHIT1 PTH1R 766/4885NPY2R 2599/4885NPY4R 3742/4885
US-12590975-B2 Methods and compositions for diagnosis and prognosis of renal injury and renal failure IGFBP6, IGFBP1, IGFBP3 PTH1R 201/4885NPY2R 1392/4885NPY4R 1501/4885
US-12590131-B2 Antimicrobial peptides with alpha-core helices VIP, HAMP, HM13 PTH1R 127/4885NPY2R 998/4885NPY4R 781/4885
US-11561230-B2 Reference standard for BNP measurement NPPA, NPR1, NPR3 PTH1R 16/4885NPY2R 336/4885NPY4R 391/4885
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG PTH1R 3702/4885NPY2R 3500/4885NPY4R 3663/4885
US-12601746-B2 Biomarkers of renal injury CD44, HDGF, PLAUR PTH1R 266/4885NPY2R 1629/4885NPY4R 2169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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