Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22465117 | 1.00 | NLRP3 (0.47) | NLRP3DRD2TBXA2RCYP19A1CYP11B1 | |
| SCHEMBL22465523 | 0.89 | S1PR1 (0.46) | NLRP3DRD2TBXA2RCYP19A1CYP11B1 | |
| SCHEMBL29668403 | 0.89 | S1PR1 (0.46) | NLRP3DRD2TBXA2RCYP19A1CYP11B1 | |
| SCHEMBL4092820 | 0.82 | DRD2 (0.64) | DRD2TBXA2RALOX5APKCNH2TP53 | |
| SCHEMBL22481419 | 0.82 | CYP11B2 (0.50) | DRD2TBXA2RCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29668281 | 0.82 | CYP11B2 (0.50) | DRD2TBXA2RCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL20919761 | 0.80 | DRD2 (0.52) | DRD2TBXA2RCYP19A1CYP11B2ALOX5AP | |
| SCHEMBL8094795 | 0.79 | AGTR1 (0.48) | NLRP3 | |
| SCHEMBL22465561 | 0.77 | DRD2 (0.45) | DRD2TBXA2RCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL22465204 | 0.77 | TBXA2R (0.52) | DRD2TBXA2RCYP19A1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332459-B2 | Benzimidazole derivatives and their uses | TEIJIN PHARMA LIMITED (JP) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332459-B2 | Benzimidazole derivatives and their uses | TRPC6, TRPV6, TRPM6 | NLRP3 955/4885DRD2 2913/4885TBXA2R 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.