SCHEMBL2969854

SCHEMBL2969854

CNC(=O)CN(CC1CCN(Cc2ccc(-c3ccc(F)cc3)cc2Cl)CC1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.42
DRD2 P14416 1/20 0.42
DRD4 P21917 1/20 0.42
MCHR1 Q99705 3/20 0.41
CHRM4 P08173 1/20 0.40
CHKA P35790 1/20 0.39
CXCR4 P61073 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2972293 0.91 ALDH1A1 (0.42) ACHEMCHR1CHRM4
SCHEMBL2982134 0.83 CXCR4 (0.53) CXCR4
SCHEMBL2982162 0.80 POLB (0.52) ACHEMCHR1
SCHEMBL2975028 0.79 ARG1 (0.44)
SCHEMBL3592322 0.78 POLB (0.50) ACHEDRD2DRD4CHRM4CXCR4
SCHEMBL3592324 0.78 ACHE (0.47) ACHEDRD2DRD4CHKA
SCHEMBL2970167 0.77 SIGMAR1 (0.49)
SCHEMBL2970364 0.77 BCHE (0.49) ACHE
Hydrochloric Acid SCHEMBL2971261 0.76 SIGMAR1 (0.48)
SCHEMBL2969849 0.76 ACHE (0.42) ACHEDRD2DRD4MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7781590-B2 Piperidinylalkylcarbamate derivatives, methods for their preparation and the therapeutic use thereof as fatty acid amido hydrolase enzyme inhibitors SANOFI-AVENTIS (FR) 2010-08-24 US disclosed
US-20070021403-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS SANOFI-AVENTIS (FR) 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021403-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS FAAH, FAAH2, CNR2 ACHE 455/4885DRD2 1610/4885DRD4 1900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.