Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | MST1R | Q04912 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5921807 | 0.75 | LMNA (0.50) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL995326 | 0.73 | LTA4H (0.55) | KDM4EALDH1A1SMN1; SMN2RAB9ALTA4H | |
| SCHEMBL28025964 | 0.72 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2RAB9ALTA4H | |
| SCHEMBL2975488 | 0.72 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2RAB9ALTA4H | |
| Hydrogen Sulfide SCHEMBL752785 | 0.71 | LTA4H (0.53) | KDM4EALDH1A1SMN1; SMN2RAB9ALTA4H | |
| SCHEMBL2964840 | 0.69 | LTA4H (0.41) | KDM4EALDH1A1SMN1; SMN2RAB9ALTA4H | |
| SCHEMBL2975867 | 0.69 | PTPRC (0.40) | KDM4EALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6228215 | 0.68 | LTA4H (0.47) | KDM4EALDH1A1SMN1; SMN2RAB9ALTA4H | |
| SCHEMBL3626478 | 0.68 | RAB9A (0.61) | KDM4EALDH1A1SMN1; SMN2RAB9ALTA4H | |
| SCHEMBL11084798 | 0.68 | LTK (0.49) | KDM4EALDH1A1LTA4HTDP1PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7763562-B2 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-7214747-B2 | Phosphorus substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214746-B2 | Phosphorus bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-08 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |
| US-20050239981-A1 | Phosphorus bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-10-27 | — | — | US | disclosed |
| US-20050239980-A1 | Phosphorus substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239981-A1 | Phosphorus bridged metallocene compounds for olefin polymerization | PYM1, ZNF207, POLL | KDM4E 1418/4885ALDH1A1 4206/4885SMN1; SMN2 4049/4885 |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | AP2M1, AP1M1, PYM1 | KDM4E 2177/4885ALDH1A1 4332/4885SMN1; SMN2 4156/4885 |
| US-20050239980-A1 | Phosphorus substituted metallocene compounds for olefin polymerization | CCRL2, ARL1, OSBP2 | KDM4E 3216/4885ALDH1A1 4248/4885SMN1; SMN2 4055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.