Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705856 | 0.86 | KMT2A (0.36) | KMT2AMEN1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL299549 | 0.85 | MLYCD (0.43) | KMT2AMEN1MLYCDPDK1PDK2 | |
| SCHEMBL3715209 | 0.84 | KMT2A (0.44) | KMT2AMEN1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL3702064 | 0.83 | MAPT (0.43) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6720686 | 0.78 | AR (0.36) | KMT2AMEN1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL6720689 | 0.76 | MAPT (0.43) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL299222 | 0.75 | MLYCD (0.41) | KMT2AMEN1MLYCDALDH1A1LMNA | |
| SCHEMBL299472 | 0.74 | LMNA (0.47) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL3703139 | 0.74 | KMT2A (0.39) | KMT2AMEN1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL29360734 | 0.74 | KMT2A (0.39) | KMT2AMEN1L3MBTL1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427427-A1 | 4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | Syngenta Participations AG (CH) | 2012-03-14 | — | — | EP | disclosed |