SCHEMBL3132299

SCHEMBL3132299

O=S(=O)(OC(c1ccccc1)(c1ccccc1)c1ccccc1)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.47
CA1 P00915 1/20 0.47
CA5A P35218 1/20 0.47
CA9 Q16790 1/20 0.47
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
PTPN1 P18031 3/20 0.39
KIF11 P52732 2/20 0.36
HSD11B1 P28845 3/20 0.34
MAPK1 P28482 1/20 0.33
GPR3 P46089 1/20 0.33
NR3C1 P04150 1/20 0.33
PGR P06401 1/20 0.33
AR P10275 1/20 0.33
ESR2 Q92731 1/20 0.33
KCNN4 O15554 2/20 0.32
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
CES1 P23141 1/20 0.32
PSIP1 O75475 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6521107 0.86 HSD11B1 (0.43) ALDH1A1KIF11HSD11B1
SCHEMBL3988445 0.81 CA2 (0.45) CA2CA1CA5ACA9ALDH1A1
SCHEMBL29449807 0.76 TSHR (0.41) CA2CA1CA5ACA9ALDH1A1
SCHEMBL5275741 0.76 CA2 (0.48) CA2CA1CA5ACA9KIF11
SCHEMBL30804417 0.74 HTR6 (0.42) CA2CA1CA5ACA9ALDH1A1
SCHEMBL780030 0.70 CA1 (0.56) CA2CA1CA5ACA9TSHR
SCHEMBL8821206 0.70 CA1 (0.56) CA2CA1CA5ACA9TSHR
SCHEMBL2990556 0.70 CA1 (0.57) CA2CA1CA5ACA9ALDH1A1
Diphenylsulfane SCHEMBL7909499 0.69 PTGS1 (0.40) CA2CA1CA5ACA9ALDH1A1
SCHEMBL12960114 0.69 CA2 (0.47) CA2CA1CA5ACA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110627686-A Synthesis method of fluorenylmethyloxycarbonyl-O-trityl-L-threonine 上海吉奉生物科技有限公司 2019-12-31 CN claimed
US-20250179109-A1 5'-MODIFIED NUCLEOSIDE AND NUCLEOTIDE USING SAME OSAKA UNIVERSITY (JP) 2025-06-05 US disclosed
EP-4488281-A1 5'-MODIFIED NUCLEOSIDE AND NUCLEOTIDE USING SAME OSAKA UNIVERSITY (JP) 2025-01-08 EP disclosed
WO-2023167094-A1 5'-MODIFIED NUCLEOSIDE AND NUCLEOTIDE USING SAME 国立大学法人大阪大学 2023-09-07 WO disclosed
US-11542350-B2 Binuclear olefin polymerization activators DOW GLOBAL TECHNOLOGIES LLC (US) 2023-01-03 US disclosed
EP-3774941-B1 BINUCLEAR OLEFIN POLYMERIZATION ACTIVATORS DOW GLOBAL TECHNOLOGIES LLC (US) 2022-11-02 EP disclosed
US-20220324891-A1 COMPOSITIONS AND METHODS FOR PREPARING REGIO- AND STEREOSELECTIVE ALICYCLIC ALKENE ISOTOPOLOGUES AND STEREOISOTOPOMERS UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2022-10-13 US disclosed
CN-114502565-A Process for producing bicyclic phosphoramidites 第一三共株式会社 2022-05-13 CN disclosed
WO-2020257299-A1 COMPOSITIONS AND METHODS FOR PREPARING REGIO- AND STEREOSELECTIVE ALICYCLIC ALKENE ISOTOPOLOGUES AND STEREOISOTOPOMERS UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2020-12-24 WO disclosed
CN-110627686-A Synthesis method of fluorenylmethyloxycarbonyl-O-trityl-L-threonine 上海吉奉生物科技有限公司 2019-12-31 CN disclosed
CN-110627686-A Synthesis method of fluorenylmethyloxycarbonyl-O-trityl-L-threonine 上海吉奉生物科技有限公司 2019-12-31 CN disclosed
CN-104231008-B The Regioselective synthesis of nucleoside medicine 5 ' bit amino acid esters 沈阳药科大学 2017-03-01 CN disclosed
CN-104231008-A Regional selective synthesis method of nucleoside drug 5'-site amino-acid ester UNIV SHENYANG PHARMACEUTICAL 2014-12-24 CN disclosed
US-7645902-B2 Acid-catalyzed dehydrogenation of amine-boranes LOS ALAMOS NATIONAL SECURITY, LLC (US) 2010-01-12 US disclosed
US-20060292068-A1 Acid-catalyzed dehydrogenation of amine-boranes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179109-A1 5'-MODIFIED NUCLEOSIDE AND NUCLEOTIDE USING SAME RNGTT, NT5C3B, NSUN2 CA2 3074/4885CA1 4458/4885CA5A 860/4885
US-11542350-B2 Binuclear olefin polymerization activators PUF60, C9, C1S CA2 2344/4885CA1 1791/4885CA5A 3847/4885
US-20220324891-A1 COMPOSITIONS AND METHODS FOR PREPARING REGIO- AND STEREOSELECTIVE ALICYCLIC ALKENE ISOTOPOLOGUES AND STEREOISOTOPOMERS ADRA2C, HTR2C, HTR1B CA2 1787/4885CA1 1324/4885CA5A 1610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.