Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 6/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909515 | 0.86 | MAPT (0.33) | MAT2ACSNK2A2CSNK2BPRMT5CYP1A2 | |
| SCHEMBL31169429 | 0.80 | PTGES (0.36) | MAT2ACSNK2A2CSNK2BPRMT5 | |
| SCHEMBL23600987 | 0.80 | PTGES (0.36) | MAT2ACSNK2A2CSNK2BPRMT5 | |
| SCHEMBL23601318 | 0.78 | PDGFRB (0.38) | MAT2ACSNK2A2CSNK2BPRMT5CYP1A2 | |
| SCHEMBL29909480 | 0.77 | MAPT (0.34) | MAT2APRMT5CYP1A2 | |
| SCHEMBL29909800 | 0.76 | MAT2A (0.32) | MAT2APRMT5CYP1A2 | |
| SCHEMBL29909281 | 0.74 | MAT2A (0.31) | MAT2A | |
| SCHEMBL29909372 | 0.74 | MAT2A (0.31) | MAT2A | |
| SCHEMBL29909653 | 0.74 | SMN1; SMN2 (0.31) | MAT2A | |
| SCHEMBL29909947 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12054490-B2 | Diacylglycerol kinase modulating compounds | GILEAD SCIENCES, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12054490-B2 | Diacylglycerol kinase modulating compounds | DGKG, DGKB, DGKK | MAT2A 1551/4885CSNK2A2 1116/4885CSNK2B 1050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.