Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP4 | Q13107 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951484 | 0.92 | PKM (0.47) | FABP4PKMMAPK1KDM4EITGB3 | |
| SCHEMBL12238277 | 0.80 | PKM (0.41) | PKMITGB3ITGA2BUSP4USP7 | |
| SCHEMBL29950706 | 0.72 | ITGB3 (0.38) | PKMKDM4EALDH1A1ITGB3ITGA2B | |
| SCHEMBL5655124 | 0.72 | MAPK1 (0.68) | FABP4MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL18409238 | 0.71 | FABP4 (0.77) | FABP4MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL29953585 | 0.71 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL29953018 | 0.70 | MEN1 (0.52) | FABP4MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL15331955 | 0.69 | CA2 (0.42) | PKMCA1CA2 | |
| SCHEMBL27563409 | 0.69 | LMNA (0.68) | FABP4MAPK1KDM4EALDH1A1LMNA | |
| SCHEMBL9717451 | 0.68 | MAPK1 (0.85) | FABP4MAPK1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |