Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951484 | 0.73 | PKM (0.47) | HDAC8L3MBTL1KDM4ELMNA | |
| SCHEMBL29954724 | 0.71 | FABP4 (0.48) | ALDH1A1HPGDKDM4ELMNASMN1; SMN2 | |
| SCHEMBL29957675 | 0.71 | SMYD3 (0.40) | ALDH1A1ALDH2BRD4L3MBTL1HSD17B10 | |
| SCHEMBL2361283 | 0.70 | CYP2C9 (0.51) | ARHDAC8HSD17B10KDM4EMEN1 | |
| SCHEMBL3785929 | 0.68 | HPGD (0.64) | ALDH1A1ALDH2L3MBTL1PPARGHPGD | |
| SCHEMBL12677941 | 0.68 | HPGD (0.45) | ALDH1A1ARBRD4L3MBTL1HSD17B10 | |
| SCHEMBL2568515 | 0.67 | APOBEC3A (0.42) | ALDH1A1ARL3MBTL1HSD17B10HPGD | |
| SCHEMBL11063029 | 0.66 | CYP1A2 (0.55) | HDAC8L3MBTL1HSD17B10GAAKDM4E | |
| SCHEMBL29950706 | 0.66 | ITGB3 (0.38) | ALDH1A1HDAC8KDM4ETSHRMEN1 | |
| SCHEMBL5206489 | 0.66 | PKM (0.51) | ALDH1A1ARBRD4HDAC8HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |