Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 3/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957654 | 0.88 | ALDH1A1 (0.39) | MAPK14MAPTALDH1A1LMNAHPGD | |
| SCHEMBL29955797 | 0.85 | KDM4E (0.38) | MAPK14MAPTKDM4EALDH1A1PARP1 | |
| SCHEMBL2558538 | 0.85 | PTGS2 (0.36) | MAPK14ALDH1A1SSTR5MEN1AHR | |
| SCHEMBL2559858 | 0.82 | GPR17 (0.35) | MAPTPARP1MEN1AHRKMT2A | |
| SCHEMBL2559831 | 0.81 | PTGS2 (0.34) | MAPTPARP1MEN1AHRKMT2A | |
| SCHEMBL29953952 | 0.81 | KDM4E (0.37) | MAPK14MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL29952426 | 0.80 | LMNA (0.40) | CSNK1DCSNK1EMAPK14MAPTKDM4E | |
| SCHEMBL2555325 | 0.80 | AHR (0.35) | MAPTKDM4EHPGDPARP1NPC1 | |
| SCHEMBL29950808 | 0.80 | APOL1 (0.37) | CSNK1DCSNK1EMAPK14MAPTKDM4E | |
| SCHEMBL29958596 | 0.79 | FEN1 (0.39) | CSNK1DCSNK1EMAPK14CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |