Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | ECE1 | P42892 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666899 | 0.87 | ALDH1A1 (0.34) | — | |
| SCHEMBL87944 | 0.85 | ALOX15 (0.41) | KDM4EALOX15TSHRTDP1ACMSD | |
| SCHEMBL4030743 | 0.79 | LMNA (0.38) | KDM4EALOX15TSHRTDP1ACMSD | |
| SCHEMBL3706189 | 0.79 | KDM4E (0.42) | KDM4ETSHRTDP1HCAR2LMNA | |
| SCHEMBL20744130 | 0.79 | CREBBP (0.37) | KDM4ETSHRLMNA | |
| SCHEMBL14393519 | 0.79 | MAPK1 (0.41) | KDM4ELMNA | |
| SCHEMBL311179 | 0.78 | KDM4E (0.35) | KDM4EALOX15TSHRTDP1ACMSD | |
| SCHEMBL21668044 | 0.75 | L3MBTL1 (0.30) | L3MBTL1 | |
| SCHEMBL20745198 | 0.74 | CYP1A2 (0.50) | KDM4ETSHRL3MBTL1 | |
| SCHEMBL6129574 | 0.74 | HPGDS (0.34) | KDM4EALOX15TSHRTDP1ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |