Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 5/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2952822 | 0.77 | MEN1 (0.42) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL7714920 | 0.76 | MEN1 (0.42) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3780741 | 0.75 | RXFP1 (0.43) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL2396852 | 0.75 | ALDH1A1 (0.63) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL1006953 | 0.74 | NLRP3 (0.43) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29956316 | 0.74 | NLRP3 (0.43) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL5622577 | 0.74 | MEN1 (0.45) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29954030 | 0.74 | HDAC4 (0.40) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL13742891 | 0.74 | GAA (0.74) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL12268247 | 0.73 | NCEH1 (0.46) | GAAMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |