Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955119 | 0.77 | CXCL8 (0.40) | NR3C1ALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL11571083 | 0.75 | MAPT (0.42) | NR3C1POLBALDH1A1MAPTTSHR | |
| SCHEMBL29950893 | 0.74 | PSIP1 (0.42) | NR3C1ALDH1A1MAPTTSHRTP53 | |
| SCHEMBL11506985 | 0.72 | MAPT (0.60) | POLBALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL29955140 | 0.72 | NR3C1 (0.40) | NR3C1ALDH1A1MAPTTSHRTP53 | |
| SCHEMBL8779736 | 0.70 | KCNQ2 (0.50) | POLBALDH1A1MAPTTSHRTP53 | |
| SCHEMBL29955167 | 0.70 | NR3C1 (0.39) | NR3C1ALDH1A1MAPTKCNQ2 | |
| SCHEMBL3260045 | 0.68 | ALDH1A1 (0.40) | ALDH1A1MAPTTSHRTP53GAA | |
| SCHEMBL11741095 | 0.67 | GPR35 (0.52) | ALDH1A1MAPTTSHRTP53GAA | |
| SCHEMBL2942491 | 0.66 | KCNQ2 (0.50) | POLBALDH1A1MAPTTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |