Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442154 | 1.00 | ALDH1A1 (0.45) | ALDH1A1CA1CA2ENPP2CA12 | |
| SCHEMBL4027923 | 0.95 | ADRA2A (0.42) | ALDH1A1CA1CA2ENPP2ADRA2A | |
| SCHEMBL12759201 | 0.91 | CA2 (0.43) | ALDH1A1CA1CA2ENPP2CA7 | |
| SCHEMBL8569648 | 0.79 | DRD1 (0.50) | — | |
| SCHEMBL13356016 | 0.78 | CA1 (0.34) | CA1CA2ENPP2TTR | |
| SCHEMBL2627980 | 0.77 | MAOA (0.61) | MEN1KMT2A | |
| SCHEMBL2627981 | 0.77 | MAOA (0.48) | ALDH1A1CA1CA2MEN1KMT2A | |
| SCHEMBL29951836 | 0.76 | ENPP2 (0.39) | ALDH1A1CA1CA2ENPP2TTR | |
| SCHEMBL3101723 | 0.74 | NPC1 (0.42) | ALDH1A1CA1CA2ENPP2NPC1 | |
| SCHEMBL6293921 | 0.74 | RXRA (0.40) | CA1CA2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431358-A | Pyrrolopyridines, compositions thereof and their use in medicine | 中国科学院上海药物研究所 | 2025-02-14 | — | — | CN | disclosed |
| CN-115362153-B | Azaspiro compounds as monoacylglycerol lipase modulators | 詹森药业有限公司 | 2025-01-07 | — | — | CN | disclosed |
| US-20240293559-A1 | SHP2 inhibitor, pharmaceutical composition containing the same and application thereof | BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) | 2024-09-05 | — | — | US | disclosed |
| EP-4417600-A1 | SHP2 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2024-08-21 | — | — | EP | disclosed |
| CN-118076592-A | SHP2 inhibitor, pharmaceutical composition comprising same and use thereof | 北京泰德制药股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115362153-A | Aza spiro rings as monoacylglycerol lipase modulators | 詹森药业有限公司 | 2022-11-18 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240293559-A1 | SHP2 inhibitor, pharmaceutical composition containing the same and application thereof | PTPN1, PTPN5, PTPN18 | ALDH1A1 3774/4885CA1 1543/4885CA2 477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.