SCHEMBL12759201

SCHEMBL12759201

OB(O)c1ccc2c(c1)CC2

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.43
CA1 P00915 2/20 0.43
ENPP2 Q13822 7/20 0.42
MGLL Q99685 2/20 0.39
TTR P02766 1/20 0.39
TSHR P16473 1/20 0.39
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4027923 0.91 ADRA2A (0.42) CA2CA1ENPP2TTRTSHR
SCHEMBL442154 0.91 ALDH1A1 (0.45) CA2CA1ENPP2TTRALDH1A1
SCHEMBL29956883 0.91 ALDH1A1 (0.45) CA2CA1ENPP2TTRALDH1A1
SCHEMBL8569648 0.83 DRD1 (0.50)
SCHEMBL13356016 0.82 CA1 (0.34) CA2CA1ENPP2TTR
SCHEMBL20968620 0.82 CA2 (0.34) CA2CA1ENPP2MGLLTTR
SCHEMBL21974802 0.82 CYP2A6 (0.48) CA2CA1ENPP2MGLLTTR
SCHEMBL3101723 0.78 NPC1 (0.42) CA2CA1ENPP2MGLLTTR
SCHEMBL15329663 0.78 ASIC3 (0.55)
SCHEMBL29953828 0.78 ENPP2 (0.35) CA2CA1ENPP2TTRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3822278-B1 ELECTRON-ACCEPTING COMPOUND, COMPOSITION FOR CHARGE TRANSPORT FILM, AND LIGHT-EMITTING ELEMENT USING SAME MITSUBISHI CHEM CORP (JP) 2026-05-06 EP disclosed
EP-4382516-B1 COMPOUND, COATING COMPOSITION COMPRISING SAME, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR LG CHEMICAL LTD (KR) 2025-10-29 EP disclosed
EP-4403554-B1 COMPOUND, COATING COMPOSITION COMPRISING SAME, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR LG CHEMICAL LTD (KR) 2025-09-24 EP disclosed
US-20240409493-A1 Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor LG CHEM, LTD. (KR) 2024-12-12 US disclosed
US-20240407256-A1 Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor LG CHEM, LTD. (KR) 2024-12-05 US disclosed
EP-4403554-A1 COMPOUND, COATING COMPOSITION COMPRISING SAME, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR LG Chem, Ltd. (KR) 2024-07-24 EP disclosed
EP-4382516-A1 COMPOUND, COATING COMPOSITION COMPRISING SAME, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR LG Chem, Ltd. (KR) 2024-06-12 EP disclosed
CN-117980301-A Compound, coating composition comprising the same, organic light emitting device using the same, and method for manufacturing the same 株式会社LG化学 2024-05-03 CN disclosed
CN-117957216-A Compound, coating composition comprising the same, organic light emitting device using the same, and method for manufacturing the same 株式会社LG化学 2024-04-30 CN disclosed
US-11793069-B2 Electron-accepting compound and composition for charge-transporting film, and luminescent element using same MITSUBISHI CHEMICAL CORPORATION (JP) 2023-10-17 US disclosed
US-20150191494-A1 TETRAHYDROISOQUINOLINES AND INTERMEDIATES THEREFOR ALBANY MOLECULAR RESEARCH, INC. 2015-07-09 US disclosed
EP-2770006-A1 CROSS-LINKING POLYMER AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd (JP) 2014-08-27 EP disclosed
US-20140231771-A1 CROSS-LINKING POLYMER AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. 2014-08-21 US disclosed
US-20140231771-A1 CROSS-LINKING POLYMER AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. 2014-08-21 US disclosed
US-8420811-B2 Tetrahydroisoquinolines and intermediates therefor BRISTOL-MYERS SQUIBB COMPANY (US) 2013-04-16 US disclosed
US-8420811-B2 Tetrahydroisoquinolines and intermediates therefor BRISTOL-MYERS SQUIBB COMPANY (US) 2013-04-16 US disclosed
US-20130060027-A1 TETRAHYDROISOQUINOLINES AND INTERMEDIATES THEREFOR BRISTOL-MYERS SQUIBB COMPANY (US) 2013-03-07 US disclosed
US-20130060027-A1 TETRAHYDROISOQUINOLINES AND INTERMEDIATES THEREFOR BRISTOL-MYERS SQUIBB COMPANY (US) 2013-03-07 US disclosed
US-20110077400-A1 PROCESSES FOR PREPARING TETRAHYDROISOQUINOLINES Bristol-Myers Squibb Company and Albany Molecular Research, Inc 2011-03-31 US disclosed
US-20110077400-A1 PROCESSES FOR PREPARING TETRAHYDROISOQUINOLINES Bristol-Myers Squibb Company and Albany Molecular Research, Inc 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130060027-A1 TETRAHYDROISOQUINOLINES AND INTERMEDIATES THEREFOR FARS2, TPH1, COQ8A CA2 4184/4885CA1 3329/4885ENPP2 2791/4885
US-20150191494-A1 TETRAHYDROISOQUINOLINES AND INTERMEDIATES THEREFOR FARS2, TPH1, COQ8A CA2 4184/4885CA1 3329/4885ENPP2 2791/4885
US-11793069-B2 Electron-accepting compound and composition for charge-transporting film, and luminescent element using same SLC26A3, SLC6A19, SLC29A1 CA2 1506/4885CA1 1775/4885ENPP2 2549/4885
US-20110077400-A1 PROCESSES FOR PREPARING TETRAHYDROISOQUINOLINES HTR2C, HTR3B, TPH2 CA2 3926/4885CA1 2450/4885ENPP2 2765/4885
US-20240409493-A1 Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor NOTUM, SEM1, OR51E2 CA2 4314/4885CA1 2087/4885ENPP2 4122/4885
US-20240407256-A1 Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor NOTUM, ORMDL3, SEM1 CA2 4499/4885CA1 2435/4885ENPP2 4146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.