Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852163 | 0.88 | CDC25B (0.54) | CDC25BIDO1APPPLK1EP300 | |
| SCHEMBL8147899 | 0.82 | IDO1 (0.58) | CDC25BIDO1EP300KAT8POLB | |
| SCHEMBL31116611 | 0.82 | CA1 (0.61) | IDO1EP300KAT8CA12CA1 | |
| SCHEMBL357145 | 0.82 | CA1 (0.61) | IDO1EP300KAT8CA12CA1 | |
| SCHEMBL20278436 | 0.82 | IDO1 (0.47) | CDC25BIDO1EP300KAT8CA12 | |
| SCHEMBL21783690 | 0.80 | APP (0.38) | APPPLK1POLBFABP4HTR1A | |
| SCHEMBL18540802 | 0.79 | IDO1 (0.49) | CDC25BIDO1EP300KAT8CA12 | |
| SCHEMBL360496 | 0.78 | CA1 (0.57) | APPCA12CA1CA2CA4 | |
| SCHEMBL29636384 | 0.78 | CA1 (0.57) | APPCA12CA1CA2CA4 | |
| SCHEMBL12473426 | 0.77 | CA1 (0.55) | IDO1PLK1EP300KAT8CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078214-B2 | Monocyclic thieno, pyrido, and pyrrolo pyrimidine compounds and methods of use and manufacture of same | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2021-08-03 | — | — | US | disclosed |
| US-10457688-B2 | Monocyclic thieno, pyrido, and pyrrolo pyrimidine compounds and methods of use and manufacture of same | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2019-10-29 | — | — | US | disclosed |
| US-9994586-B2 | Monocyclic, thieno, pyrido, and pyrrolo pyrimidine compounds and methods of use and manufacture of the same | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2018-06-12 | — | — | US | disclosed |
| US-20170141372-A1 | POROUS LAYER FOR NONAQUEOUS ELECTROLYTE SECONDARY BATTERY SEPARATOR, AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY LAMINATED SEPARATOR | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-18 | — | — | US | disclosed |
| WO-2017031176-A1 | MONOCYCLIC, THIENO, PYRIDO, AND PYRROLO PYRIMIDINE COMPOUNDS AND METHODS OF USE AND MANUFACTURE OF THE SAME | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2017-02-23 | — | — | WO | disclosed |
| US-20170050978-A1 | Monocyclic, Thieno, Pyrido, and Pyrrolo Pyrimidine Compounds and Methods of Use and Manufacture of the Same | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT | 2017-02-23 | — | — | US | disclosed |
| US-20130286338-A1 | Liquid Crystal Display Device and Method of Fabricating the Same | LG DISPLAY CO LTD (KR) | 2013-10-31 | — | — | US | disclosed |
| US-8278442-B2 | Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders | PROSIDION LIMITED (GB) | 2012-10-02 | — | — | US | disclosed |
| US-20100239744-A1 | PROCESS FOR PRODUCING POROUS FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-23 | — | — | US | disclosed |
| US-20100216028-A1 | LAMINATED POROUS FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-08-26 | — | — | US | disclosed |
| US-20100203326-A1 | AROMATIC LIQUID-CRYSTALLINE POLYESTER AMIDE COPOLYMER, PREPREG INCLUDING THE SAME, PREPREG LAMINATE INCLUDING THE PREPREG, METAL FILM LAMINATE INCLUDING THE PREPREG, AND PRINTED WIRING BOARD INCLUDING THE PREPREG | SAMSUNG FINE CHEMICALS CO., LTD. (KR) | 2010-08-12 | — | — | US | disclosed |
| US-20100173886-A1 | BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-07-08 | — | — | US | disclosed |
| US-20100159318-A1 | LAMINATED POROUS FILM | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2152671-A1 | BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008142454-A1 | BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2008-11-27 | — | — | WO | disclosed |
| US-20070077416-A1 | Substrate for flexible wiring and method for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-04-05 | — | — | US | disclosed |
| US-7193020-B2 | Film and laminate of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173886-A1 | BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | OPRM1, OPRK1, OPRD1 | CDC25B 4612/4885IDO1 599/4885APP 4321/4885 |
| US-11078214-B2 | Monocyclic thieno, pyrido, and pyrrolo pyrimidine compounds and methods of use and manufacture of same | DPYD, TYMS, THPO | CDC25B 341/4885IDO1 1580/4885APP 4153/4885 |
| US-10457688-B2 | Monocyclic thieno, pyrido, and pyrrolo pyrimidine compounds and methods of use and manufacture of same | DPYD, TPX2, TYMS | CDC25B 430/4885IDO1 1194/4885APP 3764/4885 |
| US-20170050978-A1 | Monocyclic, Thieno, Pyrido, and Pyrrolo Pyrimidine Compounds and Methods of Use and Manufacture of the Same | CYP4F3, TYMS, DPYD | CDC25B 2063/4885IDO1 765/4885APP 4559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.