Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MTTP | P55157 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29968438 | 0.89 | TSHR (0.37) | CNR2CNR1MTTPPTGS2PPARG | |
| SCHEMBL29967688 | 0.88 | CNR2 (0.38) | CNR2CNR1PTGS2PPARGKDM4E | |
| SCHEMBL29967971 | 0.84 | PPARG (0.42) | PPARGP2RX3 | |
| SCHEMBL29968433 | 0.83 | CYP19A1 (0.39) | CNR2CNR1PTGS2PPARGP2RX3 | |
| SCHEMBL29968012 | 0.82 | NR1H4 (0.46) | PPARGKDM4EP2RX3MEN1KMT2A | |
| SCHEMBL29967912 | 0.82 | P2RX3 (0.39) | CNR2PPARGP2RX3 | |
| SCHEMBL29967780 | 0.81 | PPARG (0.45) | FABP4PPARGKDM4EACMSDALDH1A1 | |
| SCHEMBL29967953 | 0.80 | PLA2G10 (0.41) | FABP4PPARGP2RX3KMT2A | |
| SCHEMBL29968198 | 0.80 | DCTPP1 (0.42) | PPARGP2RX3 | |
| SCHEMBL29967824 | 0.79 | KDM4E (0.49) | CNR2CNR1PTGS2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |