Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 5/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19617651 | 1.00 | GABRA1 (0.37) | GABRA1GABRB1GABRB2MEN1CYP1A2 | |
| SCHEMBL19121870 | 0.84 | GABRA1 (0.41) | GABRA1GABRB1GABRB2MEN1CYP1A2 | |
| SCHEMBL24133302 | 0.81 | LMNA (0.40) | MEN1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL30285983 | 0.80 | GABRA1 (0.43) | GABRA1GABRB1GABRB2MEN1KMT2A | |
| SCHEMBL6774835 | 0.80 | GABRA1 (0.43) | GABRA1GABRB1GABRB2MEN1KMT2A | |
| SCHEMBL27645331 | 0.79 | GAA (0.45) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17034855 | 0.79 | GAA (0.40) | GABRA1GABRB1CYP1A2LMNATHRB | |
| SCHEMBL282475 | 0.79 | ALDH1A1 (0.47) | GABRA1GABRB1MEN1CYP3A4CYP2C9 | |
| SCHEMBL18030223 | 0.78 | CYP1A2 (0.39) | GABRA1GABRB1GABRB2MEN1CYP1A2 | |
| SCHEMBL16978288 | 0.78 | NPSR1 (0.37) | MEN1KMT2ALMNAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916214-A | Thyromimetic agents | 速通医疗公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115279359-A | Novel thyromimetic agents | 速通医疗公司 | 2022-11-01 | — | — | CN | disclosed |