SCHEMBL29975279

SCHEMBL29975279

CCN(CC)CC.CCN(CC)CC.Cc1cn([C@H]2CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)C[C@@H](CP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TYMP P19971 4/20 0.44
NT5M Q9NPB1 1/20 0.42
TK1 P04183 6/20 0.41
LMNA P02545 2/20 0.41
TSHR P16473 2/20 0.41
ALB P02768 1/20 0.41
PKM P14618 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
CYP2D6 P10635 1/20 0.41
RNASE1 P07998 1/20 0.40
TK2 O00142 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27157713 0.95 TYMP (0.48) TYMPNT5MTK1RNASE1TK2
SCHEMBL29129493 0.89 NT5M (0.42) NT5MTK1LMNATSHRALB
SCHEMBL19660825 0.85 TK1 (0.45) TK1RNASE1TK2
SCHEMBL27157933 0.84 TK1 (0.41) TYMPNT5MTK1RNASE1
SCHEMBL441127 0.84 RNASE1 (0.50) TK1LMNATSHRALBPKM
SCHEMBL409820 0.84 RNASE1 (0.50) TK1LMNATSHRALBPKM
SCHEMBL29975987 0.83 NT5M (0.38) TYMPNT5MTK1RNASE1TK2
SCHEMBL19953995 0.82 TK1 (0.44) TK1RNASE1TK2
SCHEMBL30177217 0.82 NT5M (0.41) NT5MTK1LMNAALBPKM
SCHEMBL23713976 0.80 TK1 (0.44) NT5MTK1RNASE1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2024-08-01 US disclosed
EP-4332111-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND Nippon Shinyaku Co., Ltd. (JP) 2024-03-06 EP disclosed
WO-2022230954-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND 日本新薬株式会社 2022-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND POLRMT, CYC1, MRM1 TYMP 319/4885NT5M 2378/4885TK1 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.