Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 7/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127681 | 1.00 | MEP1B (0.52) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL6209362 | 0.86 | MEP1B (0.54) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL1762329 | 0.85 | CCR2 (0.44) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL1942107 | 0.85 | HSD11B1 (0.40) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL6536620 | 0.84 | KIF11 (0.42) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL2952580 | 0.83 | CA2 (0.62) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL172392 | 0.83 | CCR2 (0.58) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL10763658 | 0.83 | MEP1B (0.55) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27767307 | 0.81 | MEP1B (0.54) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL67150 | 0.81 | CCR2 (0.45) | CCR2LMNAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858879-A | CDK2/4/6 inhibitor and preparation method and application thereof | 南京再明医药有限公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2023031308-A1 | CCR2 INHIBITORS | ARTICA THERAPEUTICS B.V. (NL) | 2023-03-09 | — | — | WO | disclosed |
| CN-115768750-A | GCN2 modulator compounds | 阿莱斯塔治疗公司 | 2023-03-07 | — | — | CN | disclosed |
| EP-4107146-A1 | GCN2 MODULATOR COMPOUNDS | Alesta Therapeutics BV (NL) | 2022-12-28 | — | — | EP | disclosed |
| WO-2022234867-A1 | SULFONAMIDE HAVING MMP 7-INHIBITING ACTION | 大正製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |