Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 7/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29989656 | 1.00 | MEP1B (0.52) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL6209362 | 0.86 | MEP1B (0.54) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL1762329 | 0.85 | CCR2 (0.44) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL1942107 | 0.85 | HSD11B1 (0.40) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL6536620 | 0.84 | KIF11 (0.42) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL2952580 | 0.83 | CA2 (0.62) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL172392 | 0.83 | CCR2 (0.58) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL10763658 | 0.83 | MEP1B (0.55) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27767307 | 0.81 | MEP1B (0.54) | MEP1BTSHRSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL67150 | 0.81 | CCR2 (0.45) | CCR2LMNAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745312-B2 | Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation | CHEMOCENTRYX, INC. (US) | 2017-08-29 | — | — | US | claimed |
| US-20170022205-A1 | FUSED HETEROARYL PYRIDYL AND PHENYL BENZENESUFLONAMIDES AS CCR2 MODULATORS FOR THE TREATMENT OF INFLAMMATION | CHEMOCENTRYX, INC. (US) | 2017-01-26 | — | — | US | claimed |
| US-12630529-B2 | GCN2 modulator compounds | Alesta Therapeutics BV (NL) | 2026-05-19 | — | — | US | disclosed |
| WO-2025216628-A1 | PROTAC COMPOUNDS | UNIVERSITEIT LEIDEN (NL) | 2025-10-16 | — | — | WO | disclosed |
| EP-3500257-B1 | KINASE INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING CANCER | ICAHN SCHOOL MED MOUNT SINAI (US) | 2025-07-02 | — | — | EP | disclosed |
| CN-117858879-A | CDK2/4/6 inhibitor and preparation method and application thereof | 南京再明医药有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117586190-A | Benzimidazole compound containing substituted benzenesulfonyl or salt thereof, preparation method, insecticidal acaricide, parasite control agent and application | 青岛康乔药业集团有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117362256-A | Costunolide derivative as well as preparation method and application thereof | 云南中医药大学 | 2024-01-09 | — | — | CN | disclosed |
| CN-116606292-A | Pyrido [1,2-a ] pyrimidinone derivatives containing sulfonamide unit, preparation method and application thereof | 贵州大学 | 2023-08-18 | — | — | CN | disclosed |
| US-20230143059-A1 | GCN2 MODULATOR COMPOUNDS | Alesta Therapeutics BV (NL) | 2023-05-11 | — | — | US | disclosed |
| US-20230143059-A1 | GCN2 MODULATOR COMPOUNDS | Alesta Therapeutics BV (NL) | 2023-05-11 | — | — | US | disclosed |
| EP-1174028-A1 | SULFONAMIDE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |
| US-4918106-A | SOIL BORNE DISEASES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-04-17 | — | — | US | disclosed |
| US-4870107-A | N-(2-chloro-4-nitrophenyl)-(benzenesulfonamide derivative and agricultural fungicide containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1989-09-26 | — | — | US | disclosed |
| US-4851445-A | N-(2-Chloro-4-nitrophenyl)-benezene-sulfonamide derivative and agricultural fungicide containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0306222-A2 | Benzenesulfonanilide derivatives and fungicides for agriculture and horticulture | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1989-03-08 | — | — | EP | disclosed |
| EP-0199433-B1 | AN N-(2-CHLORO-4-NITROPHENYL)-BENZENESULFONAMIDE DERIVATIVE, PROCESS OF PREPARING IT AND AGRICULTURAL FUNGICIDE CONTAINING IT | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-11-23 | — | — | EP | disclosed |
| US-4737522-A | N-sulphenylated benzenesulphonic acid amide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-12 | — | — | US | disclosed |
| EP-0199433-A1 | An N-(2-chloro-4-nitrophenyl)-benzenesulfonamide derivative, process of preparing it and agricultural fungicide containing it | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-10-29 | — | — | EP | disclosed |
| US-4507315-A | Hypoglycaemic and hypolipidaemic benzamide substituted (1H-) imidazole derivatives and compositions | MAY & BAKER LIMITED (GB) | 1985-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630529-B2 | GCN2 modulator compounds | NR3C1, GCN1, EIF2AK4 | MEP1B 1951/4885TSHR 1115/4885SMN1; SMN2 2140/4885 |
| US-20230143059-A1 | GCN2 MODULATOR COMPOUNDS | EIF2AK4, GPR119, GCN1 | MEP1B 3170/4885TSHR 1868/4885SMN1; SMN2 999/4885 |
| US-20170022205-A1 | FUSED HETEROARYL PYRIDYL AND PHENYL BENZENESUFLONAMIDES AS CCR2 MODULATORS FOR THE TREATMENT OF INFLAMMATION | CCR2, CXCR2, CX3CR1 | MEP1B 3435/4885TSHR 1442/4885SMN1; SMN2 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.