Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.57 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | DDT | P30046 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2952064 | 0.83 | LDHA (0.56) | LDHANPC1RAB9ASRD5A2RXRA | |
| SCHEMBL1416558 | 0.81 | KDM1A (0.61) | KMODHODHKDM4EALDH1A1 | |
| SCHEMBL31243316 | 0.81 | LDHA (0.77) | LDHAKMONPC1RAB9ARXRA | |
| SCHEMBL7140833 | 0.81 | KMO (0.60) | MRGPRX4KMOMEN1KMT2ANPC1 | |
| SCHEMBL27956294 | 0.80 | HSD17B1 (0.63) | RAB9A | |
| SCHEMBL29917363 | 0.80 | DHODH (0.71) | MRGPRX4KMODHODHAKR1C3AKR1C2 | |
| SCHEMBL177453 | 0.80 | DHODH (0.71) | MRGPRX4KMODHODHAKR1C3AKR1C2 | |
| SCHEMBL7102932 | 0.79 | RAB9A (0.52) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3180184 | 0.79 | CYP11B1 (0.55) | LDHAKMT2ANPC1RAB9AKDM4E | |
| SCHEMBL30775369 | 0.78 | KMO (0.65) | MRGPRX4KMOMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335050-A | Compounds and compositions for treating skin conditions | 卡玛瑞制药有限公司 | 2022-11-11 | — | — | CN | disclosed |