SCHEMBL30007287

SCHEMBL30007287

O=P(O)(O)O[C@H]1C(OP(=O)(O)OP(=O)(O)O)O[C@H](CO)[C@H]1O.[Na+].[Na+].[Na+].[Na+].[Na+]

nearest known ligand 0.51

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADORA1 known ✓ P30542 1/20 0.38
SMPD1 P17405 1/20 0.39
ITPR3 Q14573 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22393 0.98 SMPD1 (0.40) SMPD1ADORA1ITPR3
Pyrophosphoric Acid SCHEMBL7582145 0.97 SMPD1 (0.39) SMPD1ADORA1ITPR3
SCHEMBL30360450 0.94 P2RY14 (0.39)
SCHEMBL4143599 0.88 SMPD1 (0.47) SMPD1ITPR3
SCHEMBL29656742 0.84 P2RY14 (0.47)
SCHEMBL3360274 0.84 P2RY14 (0.47)
SCHEMBL7541741 0.83 P2RY14 (0.49)
SCHEMBL7568791 0.83 P2RY14 (0.49)
SCHEMBL7568898 0.83 P2RY14 (0.49)
SCHEMBL7568905 0.83 P2RY14 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023074687-A1 METHOD FOR MEASURING PYROPHOSPHORIC ACID OR PHOSPHORIBOSYL PYROPHOSPHATE, MEASUREMENT COMPOSITION AND REAGENT KIT FOR MEASURING SAME, AND AMPLIFICATION METHOD THEREOF 旭化成ファーマ株式会社 2023-05-04 WO disclosed
WO-2022217695-A1 PREPARATION METHOD FOR MONONUCLEOTIDE OF NICOTINIC ACID OR DERIVATIVE THEREOF AND BIOLOGICAL PRODUCT OF MONONUCLEOTIDE 百瑞全球有限公司 2022-10-20 WO disclosed