Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155157 | 1.00 | CA12 (0.42) | CA12CA14APLNRDGAT1CA2 | |
| SCHEMBL3008075 | 1.00 | CA12 (0.42) | CA12CA14APLNRDGAT1CA2 | |
| Hydrochloric Acid SCHEMBL3014916 | 0.98 | CA12 (0.41) | CA12CA14APLNRDGAT1CA2 | |
| Oxalic Acid SCHEMBL16148596 | 0.95 | CA12 (0.40) | CA12CA14APLNRDGAT1CA2 | |
| Oxalic Acid SCHEMBL16148595 | 0.95 | CA12 (0.40) | CA12CA14APLNRDGAT1CA2 | |
| SCHEMBL13984531 | 0.83 | MEN1 (0.42) | CA12CA14APLNRCA2CA1 | |
| SCHEMBL21612221 | 0.83 | MEN1 (0.42) | CA12CA14APLNRCA2CA1 | |
| SCHEMBL12467107 | 0.83 | MEN1 (0.42) | CA12CA14APLNRCA2CA1 | |
| SCHEMBL16855011 | 0.80 | APLNR (0.41) | CA12CA14APLNRDGAT1CA2 | |
| SCHEMBL17035397 | 0.79 | CA12 (0.47) | CA12CA14APLNRDGAT1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3817742-B1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | TEMMUNE THERAPEUTICS NV (BE) | 2026-04-08 | — | — | EP | disclosed |
| US-20250082609-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Metrion Biosciences Limited (GB) | 2025-03-13 | — | — | US | disclosed |
| US-12128028-B2 | Heterocyclic sulfonamide derivatives and pharmaceutical uses thereof | Metrion Biosciences Limited (GB) | 2024-10-29 | — | — | US | disclosed |
| CN-112689509-B | Heterocyclic sulfonamide derivatives and pharmaceutical uses thereof | 梅特恩生物科学有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20210275499-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Metrion Biosciences Limited (GB) | 2021-09-09 | — | — | US | disclosed |
| CN-112689509-A | Heterocyclic sulfonamide derivatives and pharmaceutical use thereof | 梅特恩生物科学有限公司 | 2021-04-20 | — | — | CN | disclosed |
| WO-2020008206-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Metrion Biosciences Limited (GB) | 2020-01-09 | — | — | WO | disclosed |
| US-9617256-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-9617256-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20170088549-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2017-03-30 | — | — | US | disclosed |
| EP-2170814-B1 | ANTIBACTERIAL AGENTS | ACHAOGEN INC (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2170814-B1 | ANTIBACTERIAL AGENTS | ACHAOGEN INC (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2662353-A2 | Antibacterial agents | Achaogen, Inc. (US) | 2013-11-13 | — | — | EP | disclosed |
| EP-2662353-A2 | Antibacterial agents | Achaogen, Inc. (US) | 2013-11-13 | — | — | EP | disclosed |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
| CN-101765585-A | Antibacterial agent | ACHAOGEN INC | 2010-06-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250082609-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | STS, SQOR, SULT2A1 | CA12 395/4885CA14 316/4885APLNR 1886/4885 |
| US-12128028-B2 | Heterocyclic sulfonamide derivatives and pharmaceutical uses thereof | STS, SQOR, SULT2A1 | CA12 395/4885CA14 316/4885APLNR 1886/4885 |
| US-20170088549-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | CA12 4051/4885CA14 3029/4885APLNR 3978/4885 |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | CA12 4051/4885CA14 3029/4885APLNR 3978/4885 |
| US-20210275499-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | STS, SQOR, SULT2A1 | CA12 395/4885CA14 316/4885APLNR 1886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.