Sugi Predict

Sugi Predict / Compounds / SCHEMBL3008075

SCHEMBL3008075

SCHEMBL3008075

COC(=O)C(N)C(C)(C)NC(=O)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 2/20 0.42
▸ CA14 Q9ULX7 2/20 0.42
▸ APLNR P35414 1/20 0.37
▸ DGAT1 O75907 1/20 0.35
▸ CA2 P00918 2/20 0.35
▸ CA1 P00915 1/20 0.35
▸ CA7 P43166 1/20 0.35
▸ GAA P10253 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ CTSK P43235 2/20 0.32
▸ MAOA P21397 1/20 0.32
▸ MAOB P27338 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ PIK3CD O00329 1/20 0.32
▸ CYP1A2 P05177 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3002117 1.00 CA12 (0.42) CA12CA14APLNRDGAT1CA2
SCHEMBL155157 1.00 CA12 (0.42) CA12CA14APLNRDGAT1CA2
Hydrochloric Acid SCHEMBL3014916 0.98 CA12 (0.41) CA12CA14APLNRDGAT1CA2
Oxalic Acid SCHEMBL16148596 0.95 CA12 (0.40) CA12CA14APLNRDGAT1CA2
Oxalic Acid SCHEMBL16148595 0.95 CA12 (0.40) CA12CA14APLNRDGAT1CA2
SCHEMBL13984531 0.83 MEN1 (0.42) CA12CA14APLNRCA2CA1
SCHEMBL21612221 0.83 MEN1 (0.42) CA12CA14APLNRCA2CA1
SCHEMBL12467107 0.83 MEN1 (0.42) CA12CA14APLNRCA2CA1
SCHEMBL16855011 0.80 APLNR (0.41) CA12CA14APLNRDGAT1CA2
SCHEMBL17035397 0.79 CA12 (0.47) CA12CA14APLNRDGAT1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827612-B2 Hydroxamic acid derivative, method for producing same and use thereof INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2023-11-28 — — US claimed
EP-4071134-A1 HYDROXAMIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) 2022-10-12 — — EP claimed
US-20220033369-A1 HYDROXAMIC ACID DERIVATIVE, METHOD FOR PRODUCING SAME AND USE THEREOF INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2022-02-03 — — US claimed
CN-110563611-B Hydroxamic acid derivative and preparation method and application thereof 中国医学科学院医药生物技术研究所 2021-02-02 — — CN claimed
CN-111233730-A Hydroxamic acid derivative, preparation method and application 中国医学科学院医药生物技术研究所 2020-06-05 — — CN claimed
CN-110563611-A hydroxamic acid derivative and preparation method and application thereof 中国医学科学院医药生物技术研究所 2019-12-13 — — CN claimed
CN-112689509-B Heterocyclic sulfonamide derivatives and pharmaceutical uses thereof 梅特恩生物科学有限公司 2024-03-29 — — CN disclosed
US-11827612-B2 Hydroxamic acid derivative, method for producing same and use thereof INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2023-11-28 — — US disclosed
US-20230000813-A1 COMPOUND FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE INTERVET INC. (US) 2023-01-05 — — US disclosed
US-11498909-B2 Compound acting as antibiotics KBP BIOSCIENCES CO., LTD. (CN) 2022-11-15 — — US disclosed
EP-4071134-A1 HYDROXAMIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) 2022-10-12 — — EP disclosed
US-20220033369-A1 HYDROXAMIC ACID DERIVATIVE, METHOD FOR PRODUCING SAME AND USE THEREOF INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2022-02-03 — — US disclosed
CN-112689509-A Heterocyclic sulfonamide derivatives and pharmaceutical use thereof 梅特恩生物科学有限公司 2021-04-20 — — CN disclosed
US-20100190766-A1 ANTIBACTERIAL AGENTS ACHAOGEN, INC. (US) 2010-07-29 — — US disclosed
US-20100190766-A1 ANTIBACTERIAL AGENTS ACHAOGEN, INC. (US) 2010-07-29 — — US disclosed
US-20100190766-A1 ANTIBACTERIAL AGENTS ACHAOGEN, INC. (US) 2010-07-29 — — US disclosed
CN-101765585-A Antibacterial agent ACHAOGEN INC 2010-06-30 — — CN disclosed
EP-2170814-A2 ANTIBACTERIAL AGENTS Achaogen, Inc. (US) 2010-04-07 — — EP disclosed
WO-2008154642-A2 ANTIBACTERIAL AGENTS ACHAOGEN, INC. (US) 2008-12-18 — — WO disclosed
WO-2008154642-A2 ANTIBACTERIAL AGENTS ACHAOGEN, INC. (US) 2008-12-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11498909-B2 Compound acting as antibiotics PEPD, NRDC, DPP4 CA12 2988/4885CA14 2312/4885APLNR 3390/4885
US-20100190766-A1 ANTIBACTERIAL AGENTS MRPL21, SI, ABCB11 CA12 4051/4885CA14 3029/4885APLNR 3978/4885
US-20220033369-A1 HYDROXAMIC ACID DERIVATIVE, METHOD FOR PRODUCING SAME AND USE THEREOF HACL2, NAAA, LCT CA12 792/4885CA14 1025/4885APLNR 2006/4885
US-20230000813-A1 COMPOUND FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE PIGS, BTD, BRD1 CA12 2041/4885CA14 1826/4885APLNR 2986/4885
US-11827612-B2 Hydroxamic acid derivative, method for producing same and use thereof HACL2, NAAA, LCT CA12 792/4885CA14 1025/4885APLNR 2006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.