Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | MC5R | P33032 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174430 | 1.00 | NPC1 (0.46) | NPC1RAB9AHPGDSMN1; SMN2DDAH1 | |
| SCHEMBL11784869 | 0.98 | NPC1 (0.45) | NPC1RAB9AHPGDSMN1; SMN2DDAH1 | |
| SCHEMBL27508347 | 0.82 | MAOB (0.44) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11784862 | 0.79 | PSMB8 (0.44) | NPC1RAB9AHPGDSMN1; SMN2DDAH1 | |
| SCHEMBL30943481 | 0.72 | HPGD (0.57) | NPC1RAB9AHPGDSMN1; SMN2DDAH1 | |
| SCHEMBL1001902 | 0.72 | HPGD (0.57) | NPC1RAB9AHPGDSMN1; SMN2DDAH1 | |
| SCHEMBL14413949 | 0.70 | HPGD (0.51) | NPC1RAB9AHPGDSMN1; SMN2DDAH1 | |
| SCHEMBL999631 | 0.70 | HPGD (0.51) | NPC1RAB9AHPGDSMN1; SMN2DDAH1 | |
| SCHEMBL13369306 | 0.70 | LOXL2 (0.54) | NPC1RAB9AHPGDSMN1; SMN2DDAH1 | |
| SCHEMBL569032 | 0.69 | ALDH1A1 (0.67) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116159076-A | Functionalized manganese doped mesoporous nanomaterial and preparation method and application thereof | 上海师范大学 | 2023-05-26 | — | — | CN | claimed |
| CN-116159076-B | Functionalized manganese doped mesoporous nanomaterial and preparation method and application thereof | 上海师范大学 | 2025-08-26 | — | — | CN | disclosed |
| US-20250129050-A1 | SYNTHESIS OF A KIF18A INHIBITOR | AMGEN INC. (US) | 2025-04-24 | — | — | US | disclosed |
| EP-4469437-A1 | SYNTHESIS OF A KIF18A INHIBITOR | Amgen Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-118922406-A | Synthesis of KIF18A inhibitors | 安进公司 | 2024-11-08 | — | — | CN | disclosed |
| WO-2023146973-A1 | SYNTHESIS OF A KIF18A INHIBITOR | AMGEN INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| CN-116159076-A | Functionalized manganese doped mesoporous nanomaterial and preparation method and application thereof | 上海师范大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-116159076-A | Functionalized manganese doped mesoporous nanomaterial and preparation method and application thereof | 上海师范大学 | 2023-05-26 | — | — | CN | disclosed |
| EP-4110397-A1 | SYSTEMS AND METHODS FOR PROTECTING NUCLEIC-ACID MOLECULES | The Board of Trustees of the Leland Stanford Junior University (US) | 2023-01-04 | — | — | EP | disclosed |
| CN-113368235-B | Gd-NGQDs/BTS @ PLGA-PEG nano material and preparation method and application thereof | 上海师范大学 | 2022-11-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129050-A1 | SYNTHESIS OF A KIF18A INHIBITOR | KIF18A, KIF18B, KIF15 | NPC1 584/4885RAB9A 105/4885HPGD 3393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.