Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.53 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.53 |
| ▸ | SCN1A known ✓ | P35498 | 2/20 | 0.37 |
| ▸ | SCN2A known ✓ | Q99250 | 2/20 | 0.37 |
| ▸ | SCN3A known ✓ | Q9NY46 | 2/20 | 0.37 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30774612 | 1.00 | CA12 (0.53) | CA12CA3CA4CA6CA5A | |
| SCHEMBL3384281 | 1.00 | CA12 (0.53) | CA12CA3CA4CA6CA5A | |
| Water SCHEMBL25181635 | 0.98 | CA12 (0.51) | CA12CA3CA4CA6CA5A | |
| SCHEMBL6254 | 0.83 | CA12 (0.54) | CA12CA3CA4CA6CA5A | |
| SCHEMBL29349851 | 0.83 | CA12 (0.54) | CA12CA3CA4CA6CA5A | |
| Hydrochloric Acid SCHEMBL14833086 | 0.82 | TSHR (0.55) | CA12CA3CA4CA6CA5A | |
| SCHEMBL3384286 | 0.82 | CA12 (0.53) | CA12CA3CA4CA6CA5A | |
| SCHEMBL3384278 | 0.82 | CA12 (0.53) | CA12CA3CA4CA6CA5A | |
| SCHEMBL29018091 | 0.81 | CA12 (0.47) | CA12CA3CA4CA6CA5A | |
| SCHEMBL30461559 | 0.81 | CA12 (0.47) | CA12CA3CA4CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230358677-A1 | Reversible Excited-State Photoacids and Photobases as Dynamic Fluorescence Sensors of Protonic Species | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-11-09 | — | — | US | claimed |
| CN-115261995-A | Crystal face micro-structuring auxiliary agent and preparation method and application thereof | 陕西科技大学 | 2022-11-01 | — | — | CN | claimed |
| EP-3430015-B1 | METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR | ORYZON GENOMICS SA (ES) | 2025-08-06 | — | — | EP | disclosed |
| US-12195783-B2 | Methods to determine KDM1A target engagement and chemoprobes useful therefor | ORYZON GENOMICS S.A. (ES) | 2025-01-14 | — | — | US | disclosed |
| CN-116430055-B | T cell immunological state marker combination for evaluating chronic pathological state of T lymphocyte of disease and application thereof | 中南大学湘雅二医院 | 2024-07-30 | — | — | CN | disclosed |
| CN-118139872-A | Esterified protein and method for producing the same | 丝芭博株式会社 | 2024-06-04 | — | — | CN | disclosed |
| US-20230358677-A1 | Reversible Excited-State Photoacids and Photobases as Dynamic Fluorescence Sensors of Protonic Species | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-11-09 | — | — | US | disclosed |
| CN-116430055-A | T cell immunological state marker combination for evaluating chronic pathological state of T lymphocyte of disease and application thereof | 中南大学湘雅二医院 | 2023-07-14 | — | — | CN | disclosed |
| CN-115667923-A | Blood-based complex group controls | 贝克顿·迪金森公司 | 2023-01-31 | — | — | CN | disclosed |
| US-20220389478-A1 | METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR | ORYZON GENOMICS SA (ES) | 2022-12-08 | — | — | US | disclosed |
| CN-115261995-A | Crystal face micro-structuring auxiliary agent and preparation method and application thereof | 陕西科技大学 | 2022-11-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220389478-A1 | METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR | KDM1B, KDM1A, KDM7A | CA12 2752/4885CA4 2332/4885SCN1A 2579/4885 |
| US-12195783-B2 | Methods to determine KDM1A target engagement and chemoprobes useful therefor | KDM1B, KDM1A, KDM7A | CA12 2752/4885CA4 2332/4885SCN1A 2579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.