Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880186 | 0.82 | MAOA (0.39) | MAOADRD2TSHRHSD17B10KDM4E | |
| SCHEMBL23705832 | 0.81 | MAOA (0.43) | MAOADRD2TSHRHSD17B10KDM4E | |
| SCHEMBL30097038 | 0.80 | L3MBTL1 (0.38) | L3MBTL1RAB9A | |
| SCHEMBL30097024 | 0.75 | GAA (0.38) | ALDH1A1 | |
| SCHEMBL17017128 | 0.71 | L3MBTL1 (0.46) | TSHRHSD17B10KDM4EL3MBTL1HPGD | |
| SCHEMBL17017926 | 0.69 | L3MBTL1 (0.46) | TSHRCYP2C9L3MBTL1ALDH1A1LMNA | |
| SCHEMBL30097047 | 0.68 | FAAH (0.44) | TSHRHSD17B10L3MBTL1ALDH1A1LMNA | |
| SCHEMBL22366449 | 0.67 | L3MBTL1 (0.47) | TSHRHSD17B10KDM4ECYP2C9L3MBTL1 | |
| SCHEMBL30097049 | 0.67 | MAPKAPK2 (0.42) | TSHRKDM4ECYP2C9L3MBTL1ALDH1A1 | |
| SCHEMBL30097018 | 0.67 | ATM (0.44) | TSHRHSD17B10L3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |