Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.47 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418906 | 0.87 | CCR5 (0.64) | MEN1KMT2ACCR5LMNAALDH1A1 | |
| SCHEMBL23275276 | 0.85 | MEN1 (0.56) | MEN1KMT2ACCR5LMNALRRK2 | |
| SCHEMBL30101799 | 0.83 | CCR5 (0.50) | MEN1KMT2ACCR5LMNACYP3A4 | |
| SCHEMBL30101745 | 0.82 | CCR5 (0.53) | MEN1KMT2ACCR5LMNACYP3A4 | |
| SCHEMBL30101793 | 0.80 | GAA (0.47) | MEN1KMT2ACCR5LMNAALDH1A1 | |
| SCHEMBL20869029 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2ACCR5LMNAALDH1A1 | |
| SCHEMBL30101803 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2ACCR5LMNAALDH1A1 | |
| SCHEMBL30101842 | 0.79 | CCR5 (0.47) | MEN1KMT2ACCR5LMNALRRK2 | |
| SCHEMBL479925 | 0.78 | CYP3A4 (0.72) | KMT2ALMNACYP3A4NAMPTALDH1A1 | |
| SCHEMBL30101769 | 0.77 | LMNA (0.46) | MEN1KMT2ACCR5LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411377-A1 | SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | NORTHWESTERN UNIVERSITY | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411377-A1 | SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | NOS3, NOS1, NOS2 | MEN1 4446/4885KMT2A 3078/4885CCR5 3927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.