Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.47 |
| ▸ | USP25 | Q9UHP3 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418906 | 0.88 | CCR5 (0.64) | CCR5LMNACYP1A2USP28USP25 | |
| SCHEMBL23275535 | 0.85 | LRRK2 (0.54) | CCR5LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30101804 | 0.83 | MEN1 (0.51) | CCR5LMNACYP3A4LRRK2USP28 | |
| SCHEMBL16410244 | 0.81 | CFD (0.48) | CCR5LMNAUSP28USP25ALDH1A1 | |
| SCHEMBL20869029 | 0.80 | ALDH1A1 (0.48) | CCR5LMNAMAPTMEN1KMT2A | |
| SCHEMBL30101803 | 0.80 | ALDH1A1 (0.48) | CCR5LMNAMAPTMEN1KMT2A | |
| SCHEMBL17764225 | 0.80 | CCR5 (0.44) | CCR5LMNAUSP28USP25MEN1 | |
| SCHEMBL30101842 | 0.80 | CCR5 (0.47) | CCR5LMNALRRK2USP28USP25 | |
| SCHEMBL6285264 | 0.78 | CTSS (0.56) | LMNARAB9A | |
| SCHEMBL31456961 | 0.78 | CTSS (0.56) | LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411377-A1 | SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | NORTHWESTERN UNIVERSITY | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411377-A1 | SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | NOS3, NOS1, NOS2 | CCR5 3927/4885LMNA 2172/4885CYP1A2 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.