Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30104902 | 0.85 | S100A4 (0.37) | HPGDS100A4KMT2AALDH1A1MAOB | |
| SCHEMBL30104840 | 0.83 | NR2E3 (0.37) | S100A4ALDH1A1MAOBCCKBRDAO | |
| SCHEMBL30104893 | 0.81 | CCKBR (0.41) | S100A4ALDH1A1MAOBCCKBRDAO | |
| SCHEMBL30104876 | 0.79 | CTSB (0.36) | HPGDS100A4KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30104851 | 0.77 | KMT2A (0.35) | KMT2A | |
| SCHEMBL30104905 | 0.76 | NPSR1 (0.37) | KMT2AALDH1A1DAOLMNA | |
| SCHEMBL30104898 | 0.69 | CCKBR (0.41) | HPGDS100A4KMT2AALDH1A1MAOB | |
| SCHEMBL29822164 | 0.68 | KMT2A (0.37) | KMT2A | |
| SCHEMBL30104867 | 0.67 | MAPK1 (0.47) | POLBHPGDS100A4ALDH1A1CCKBR | |
| SCHEMBL30104878 | 0.64 | NUAK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583927-B | Thioether compound, and preparation method and application thereof | 华南师范大学 | 2024-07-12 | — | — | CN | disclosed |
| CN-115583927-A | Thioether compound and preparation method and application thereof | 华南师范大学 | 2023-01-10 | — | — | CN | disclosed |